Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Obesity -- mild or severe -- raises kidney stone risk

18.02.2010
Obesity in general nearly doubles the risk of developing kidney stones, but the degree of obesity doesn't appear to increase or decrease the risk one way or the other, a new study from Johns Hopkins shows.

"The common thinking was that as weight rises, kidney stone risk rises as well, but our study refutes that," says study leader Brian R. Matlaga, assistant professor of urology at the Johns Hopkins University School of Medicine and director of stone diseases and ambulatory care at Hopkins' James Buchanan Brady Urological Institute. "Whether someone is mildly obese or morbidly obese, the risk for getting kidney stones is the same."

The findings are published in the February Journal of Urology.

Over the last decade, several epidemiological studies have shown a strong connection between obesity and kidney stone disease. However, as obesity continues to rise worldwide, Matlaga and his colleagues wondered whether different subcategories of obesity, ranging from mildly to morbidly obese, presented different risks.

To answer the question, the researchers used a national insurance claims database to identify 95,598 people who had completed a "health risk assessment" form with information about their body mass index (BMI), a measure of body fat calculated by dividing weight by height, and a general indicator of underweight, healthy weight, or overweight. The database, which spanned over a five-year period from 2002 to 2006, also had encoded information indicating whether these individuals had been diagnosed with kidney stone disease.

Using a definition of obesity as having a BMI greater than 30 kg/m2 (which, in English measurements, corresponds to a 5 foot tall person who weighs 153 pounds, or a 6 foot tall person who weighs 221 pounds), the researchers calculated the incidence of kidney stones in people who were non-obese and in those who were obese. Among the non-obese individuals, 2.6 percent were diagnosed during the study period with kidney stones, compared to 4.9 percent of the obese individuals. When the investigators arranged those in the obese group by their BMIs, ranging from above 30 kg/m2 to more than 50 kg/m2, they found that the increased risk remained constant, regardless of how heavy the individuals were.

Matlaga says that he and his colleagues aren't sure why obese people are more at risk for kidney stones, though metabolic or endocrine factors unique to obesity are likely reasons, along with dietary factors such as a high-salt diet. The researchers plan to study these potential risk factors in subsequent studies.

Other researchers who participated in this study include Michelle J. Semins, M.D., Andrew D. Shore, Ph.D., Martin A. Makary, M.D., M.P.H., Thomas Magnuson, M.D., and Roger Johns, M.D., M.P.H., all of the Johns Hopkins University School of Medicine.

For more information, go to:
http://urology.jhu.edu/kidney/stones.php
http://urology.jhu.edu/brianmatlaga/

Christen Brownlee | EurekAlert!
Further information:
http://www.jhmi.edu

Further reports about: BMI Body Mass Index Medicine kidney stone risk kidney stones obesity risk factor

More articles from Health and Medicine:

nachricht PET imaging tracks Zika virus infection, disease progression in mouse model
20.09.2017 | US Army Medical Research Institute of Infectious Diseases

nachricht 'Exciting' discovery on path to develop new type of vaccine to treat global viruses
18.09.2017 | University of Southampton

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

Im Focus: Fast, convenient & standardized: New lab innovation for automated tissue engineering & drug

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...

Im Focus: Silencing bacteria

HZI researchers pave the way for new agents that render hospital pathogens mute

Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Molecular Force Sensors

20.09.2017 | Life Sciences

Producing electricity during flight

20.09.2017 | Power and Electrical Engineering

Tiny lasers from a gallery of whispers

20.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>