Their research has shown that autonomic reflex testing, which measures involuntary changes in heart rate and blood pressure, consistently appear to demonstrate significant changes in those with concussion. They presented the findings at the American Academy of Neurology annual meeting in San Diego this week.
Right now doctors rely primarily on self-reporting of symptoms to make a diagnosis of concussion. In addition, other than the absence of symptoms, there is no reliable test to determine when an athlete's brain has fully recovered from concussion. Doctors know from brain imaging research studies, that there is a lag between when the patient reports that their symptoms have resolved and the time when the brain has actually healed. Therefore, a rapid, reliable, cost-effective tool is needed to identify full brain recovery from concussion.
"This has the potential to change the way we approach concussion patients," says David Dodick, M.D., a neurologist and director of the Mayo Clinic Concussion Program. "One of the challenges of treating someone with a concussion is to reliably make a diagnosis: to know when the brain is injured and to know when the brain is actually recovered."
"Autonomic nervous system dysfunction has long been recognized as a possible complication of people with severe traumatic brain injury but has rarely been associated with people with concussions or milder forms of brain injury," adds co-author Brent Goodman, M.D., a Mayo neurologist and autonomic expert. The autonomic nervous system acts as an involuntary control system for functions such as heart rate, blood pressure, digestion, respiratory rate and perspiration.
In the study, Mayo Clinic doctors monitored 21 consecutive patients after concussion, and all experienced significant abnormalities in heart rate and blood pressure during autonomic testing. The physicians conclude that these abnormalities are tied to the concussion.
"Contrary to popular belief, the symptoms of 'dizziness' that patients feel just after a concussion may, in some cases, be symptoms of autonomic system impairment rather than a vestibular or inner ear disturbance," says Bert Vargas, M.D., a Mayo neurologist.
More research is needed, but the Mayo team is optimistic, Dr. Dodick says.
"This study shows a possible electrophysiological biomarker that indicates that a concussion has occurred — we are hopeful that with more research this will be confirmed and that this may also be a biomarker for recovery," he says.
About Mayo Clinic
Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit MayoClinic.com or MayoClinic.org/news.
Journalists can become a member of the Mayo Clinic News Network for the latest health, science and research news and access to video, audio, text and graphic elements that can be downloaded or embedded.Media Contact
Nick Hanson | EurekAlert!
Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin
Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy