Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Interventions needed to promote healthy behaviors among perinatally HIV-infected youth

As youth infected at birth with HIV reach adolescence and young adulthood, a new study published in Clinical Infectious Diseases underscores the need to promote healthy behaviors as some of these young people become sexually active.

Like other adolescents, some of the 330 young people in the study (from 15 sites across the U.S.) have initiated sexual activity, with many reporting having unprotected sex.

Of the youth who were asked about disclosure of their HIV status to their first sexual partners, the majority reported that they had not disclosed to their partner prior to sexual activity, researchers found. While sexual activity is not uncommon among adolescents, HIV-infected or not, "HIV infection adds another level of complexity to the adolescence of youth who are infected and has implications for both their own health and that of their sexual partners," said lead study author Katherine Tassiopoulos, DSc, MPH, of the Harvard School of Public Health.

The link between not following regimens for antiretroviral therapy (ART) medications — known as non-adherence—and risky sexual behaviors, already recognized among HIV-positive adults, is just now coming to light in adolescents as this cohort emerges from childhood. "Among youth, both non-adherence and sexual initiation may be expressions of independence or of the desire to feel accepted by peers," the authors noted. Successful interventions may account for adolescents' growing desire for independence by encouraging medication adherence, disclosure, and condom use as behaviors that will protect the health of their sexual partners as well as their own.

Early action by clinicians can help prepare these youth to make choices that reduce risk to themselves and to their partners. A critical step is informing youth of their HIV status. In this study, 18 percent of the participants were unaware they were HIV-positive at the time they started sexual activity. Clinicians and families should ensure that young people with HIV are informed of their HIV status prior to or during early adolescence, according to current guidelines for disclosure of HIV infection to children and adolescents.

Researchers found that among sexually active youth with high viral load (> 5,000 copies/ml), 81 percent had drug-resistant virus. This raises the possibility of resistant virus being transmitted to sexual partners and also limits treatment options for infected youth. Author George R. Seage III, DSc, MPH, also of the Harvard School of Public Health, believes that one critical step in encouraging optimal adherence may be informing young people "that ART can dramatically reduce the likelihood of sexual transmission of HIV."

Although the three-pronged message—safer sex practices, disclosure of HIV status to sexual partners, and adherence to ART regimens—is not new, targeted and innovative intervention strategies are needed to reach this important group of adolescents and reinforce healthy behaviors, the team of authors concluded.

The study is available online. It is embargoed until 12:01 a.m. EDT on Thursday, Nov. 8, 2012:

Sexual Risk Behavior Among Youth With Perinatal HIV Infection in the United States: Predictors and Implications for Intervention Development

Clinical Infectious Diseases is a leading journal in the field of infectious disease with a broad international readership. The journal publishes articles on a variety of subjects of interest to practitioners and researchers. Topics range from clinical descriptions of infections, public health, microbiology, and immunology to the prevention of infection, the evaluation of current and novel treatments, and the promotion of optimal practices for diagnosis and treatment. The journal publishes original research, editorial commentaries, review articles, and practice guidelines and is among the most highly cited journals in the field of infectious diseases. Clinical Infectious Diseases is an official publication of the Infectious Diseases Society of America (IDSA). Based in Arlington, Va., IDSA is a professional society representing nearly 10,000 physicians and scientists who specialize in infectious diseases. For more information, visit

Jerica Pitts | EurekAlert!
Further information:

More articles from Health and Medicine:

nachricht Advanced analysis of brain structure shape may track progression to Alzheimer's disease
26.10.2016 | Massachusetts General Hospital

nachricht Indian roadside refuse fires produce toxic rainbow
26.10.2016 | Duke University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

How nanoscience will improve our health and lives in the coming years

27.10.2016 | Materials Sciences

OU-led team discovers rare, newborn tri-star system using ALMA

27.10.2016 | Physics and Astronomy

'Neighbor maps' reveal the genome's 3-D shape

27.10.2016 | Life Sciences

More VideoLinks >>>