Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Increased prevention efforts may not reduce spread of hospital-based bacteria

14.04.2011
NIH study evaluated 18 intensive care units

WHAT: Expanded use of active surveillance for bacteria and of barrier precautions—specifically, gloves and gowns—did not reduce the transmission of two important antibiotic-resistant bacteria in hospital-based settings, according to a prospective, randomized clinical trial conducted in 18 intensive care units in the United States.

Incomplete compliance by health care providers with recommended hand hygiene procedures and the use of gloves and gowns, along with time lags in confirming the presence of bacteria in patients, may have contributed to the findings, which are published in the April 14 issue of the New England Journal of Medicine. The study was primarily funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococcus (VRE) bacteria—major causes of difficult-to-treat, hospital-based infections—can be spread from patient to patient on the hands of healthcare providers and via objects and surfaces such as clothing, chairs, doorknobs and medical equipment.

In the Strategies to Reduce Transmission of Antimicrobial Resistant Bacteria in Intensive Care Units (STAR*ICU) clinical trial, one of the largest studies looking at the spread of infections in hospitals to date, researchers led by W. Charles Huskins, M.D., of the Mayo Clinic in Rochester, Minn., examined whether actively screening patients for MRSA and VRE and employing greater use of barrier precautions along with hand hygiene among healthcare workers could reduce bacteria transmission in comparison with existing ICU practices.

Active screening of culture samples identified patients not previously known to carry MRSA or VRE bacteria; however, there was no difference in the frequency of new bacteria or infection events between those patients who received care according to the expanded interventions and those in the control group who did not. Trained monitors observed that health care professionals in both the control and intervention groups practiced proper hand hygiene and used gloves and gowns less often than required.

The authors conclude that to substantially decrease the transmission of MRSA and VRE bacteria in health care settings, improved compliance with isolation precautions, recommended in some cases, may need to be coupled with interventions to reduce the presence of the bacteria on body sites and decrease environmental contamination.

More information about NIAID's multifaceted research efforts to combat antimicrobial resistance is available on the NIAID Antimicrobial (Drug) Resistance Web portal (http://www.niaid.nih.gov/topics/antimicrobialresistance/Pages/default.aspx).

ARTICLE:

WC Huskins et al. Interventions to reduce transmission of resistant bacteria in intensive care units. New England Journal of Medicine DOI: 10.1056/NEJMoa1000373 (2011).

WHO:

NIAID Director Anthony S. Fauci, M.D., and Dennis Dixon, Ph.D., chief of the Bacteriology and Mycology Branch in the Division of Microbiology and Infectious Diseases, are available to comment on this article.

CONTACT:

To schedule interviews, please contact Ann Mosher, (301) 402-1663, or moshera@niaid.nih.gov.

NIAID conducts and supports research—at NIH, throughout the United States, and worldwide—to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at http://www.niaid.nih.gov.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

Ann Mosher | EurekAlert!
Further information:
http://www.niaid.nih.gov

More articles from Health and Medicine:

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht On track to heal leukaemia
18.01.2017 | Universitätsspital Bern

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

New Study Will Help Find the Best Locations for Thermal Power Stations in Iceland

19.01.2017 | Earth Sciences

Not of Divided Mind

19.01.2017 | Life Sciences

Molecule flash mob

19.01.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>