A paper by the researchers, "3D Printing of Preclinical X-ray Computed Tomographic Data Sets," was published in the Journal of Visualized Experiments this week.
The strategy was initiated last spring by then-freshman Evan Doney, a Glynn Family Honors student in the laboratory of W. Matthew Leevy, research assistant professor at the Notre Dame Integrated Imaging Facility. "It's a very clever idea," Leevy says. "He did a lot of it independently. He figured out how to convert the tomographic data to a surface map for editing and subsequent 3D printing."
The paper reports results based on using X-ray CT data sets from a living Lobund-Wistar rat from the Freimann Life Science Center and from the preserved skull of a New Zealand White Rabbit in the laboratory of Matthew Ravosa. Coauthors of the article with Doney, Leevy, and Ravosa are Lauren Krumdick, Justin Diener, Connor Wathen, Sarah Chapman, Jeremiah Scott and Tony Van Avermaete, all of Notre Dame, and Brian Stamile of MakerBot Industries LLC, a 3-D printing company.
"With proper data collection, surface rendering, and stereolithographic editing, it is now possible and inexpensive to rapidly produce detailed skeletal and soft tissue structures from X-ray CT data," the paper says. The translation of pre-clinical 3D data to a physical object that is an exact copy of the test subject is a powerful tool for visualization and communication, especially for relating imaging research to students, or those in other fields."
"Our project with 3-D printing is part of a broader story about 3-D printing in general," Leevy says, adding that the work has spawned several more ideas and opportunities, such as providing inexpensive models for anatomy students. "There's a market for these bones, both from animals and from humans, and we can create them at incredibly low cost. We're going to explore a lot of these markets."
A clinical collaborator, Dr. Douglas Liepert from Allied Physicians of Michiana, is enabling the researchers to print non-identifiable human data, expanding the possibilities. "Not only can we print bone structure, but we're starting to collect patient data and print out the anatomical structure of patients with different disease states to aid doctors in surgical preparation," Leevy says.
Matthew Leevy | EurekAlert!
'Memtransistor' brings world closer to brain-like computing
22.02.2018 | Northwestern University
MRI technique differentiates benign breast lesions from malignancies
20.02.2018 | Radiological Society of North America
A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
23.02.2018 | Physics and Astronomy
23.02.2018 | Health and Medicine
23.02.2018 | Physics and Astronomy