But now a team of Vancouver-based researchers has identified a key predictor of mortality in CAD patients, which means that specialists can better determine how to treat and improve outcomes for patients with CAD.
Coronary artery disease is the most frequent cause of heart disease and occurs when important blood vessels become narrow or blocked and can no longer give enough blood to meet the heart's demand.
In an article published today in the prestigious Journal of the American College of Cardiology, researchers Claire Heslop, Dr. Jiri Frohlich, and Dr. John Hill from The Providence Heart + Lung Institute and the University of British Columbia detail their discovery, that high levels of an enzyme, myeloperoxidase, in the blood of CAD patients more than doubles the risk for death over a 13 year period. Myeloperoxidase is an enzyme associated with oxidative stress, which damages arterial tissue.
The research team, funded by the Heart and Stroke Foundation of BC & Yukon, looked at blood samples and records from a group of patients admitted to hospital in the early 1990s with symptoms of heart disease. Over a 13 year period, mortality was more than double for patients with high blood levels of myeloperoxidase than for those with lower levels.
Based on this work, the researchers were able to develop a new classification of risk for CAD patients based on their levels of myeloperoxidase. Measurement of the enzyme provides added predictive value for cardiovascular death when compared to traditional risk factors such as smoking and diabetes. "We hope that the discovery of new markers of cardiovascular risk will help identify specific patients who could benefit from more aggressive treatment strategies" said lead investigator, Dr. John Hill.
Patients whose records and samples were used in this study all consented to have their information used for research.
The Heart and Stroke Foundation of Canada has funded researchers across Canada for over 50 years. Every year, the Foundation presents grants, awards and scholarships to leading stroke and heart disease researchers who are committed to reducing and eliminating the effects of stroke and heart disease.
"We are proud to support Canadian researchers, such as Dr. Hill, Dr. Frohlich and Ms. Heslop , who are combining their efforts to develop new techniques to fight heart disease and identify factors in at-risk individuals," says Bobbe Wood, President and CEO of Heart and Stroke Foundation of BC & Yukon. "Since almost 40,000 deaths occur in Canada each year due to CAD, it's crucial to focus on better methods to treat such a devastating health problem."
The Heart and Stroke Foundation of Canada, a volunteer-based health charity, leads in eliminating heart disease and stroke and reducing their impact through the advancement of research and its applications, the promotion of healthy living and advocacy.
20.11.2017 | Washington University in St. Louis
Carefully crafted light pulses control neuron activity
20.11.2017 | University of Illinois at Urbana-Champaign
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.
Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...
Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...
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