Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Small synaptic impulses are the key to rapid non-linear information processing in the brain

10.09.2010
Press Release - Reported in PLoS Computational Biology, the findings offer fundamental insights relevant to a wide range of biological, physical and technical systems

A novel theoretical framework for mathematically modeling nerve cells has illuminated for the first time how small synaptic impulses enable non-linear information processing in the brain. Reported in PLoS Computational Biology, the findings offer fundamental insights relevant to a wide range of biological, physical and technical systems.

In the field of neuroscience, neurons are known to communicate via so-called gaction potentialsh, brief impulses which cause a cellfs membrane potential to rise and fall. Only when many such impulses together exceed a threshold value does the neuron gfireh, releasing its action potential to target neurons. How neurons transfer action potentials from inputs into outputs determines which elementary operations they are able to perform, and at what rate.

With their latest work, researchers at the RIKEN Brain Science Institute and Bernstein Center for Computational Neuroscience set out to resolve contradictory findings uncovered earlier regarding this input-output relationship. At issue was the conventional theory of spiking neuronal networks, which approximates impulses in the limit where they become vanishingly tiny and infinitely numerous, limiting the capabilities of individual neurons to simple addition of inputs.

Using a newly-developed high-precision method for simulating nonlinear neuron models (see references), the team had previously uncovered contradictions in this theory. To unravel this mystery, the researchers developed a new analytic framework which explicitly incorporates the finite effect of each input at the critical boundary near the firing threshold. With this change, they show that not only can neurons process information far faster than previously believed, they can also perform nonlinear operations such as multiplication that are key to complex information processing.

While more accurately capturing the network aspect of neural dynamics, the new framework also reveals how cooperation between seemingly uncoordinated input signals enables neurons to perform many non-linear operations at the same time. Future work will build on these findings toward a better understanding of brain function, a fundamental requirement for treating neural diseases.

For more information, please contact:

Dr. Markus Diesmann
RIKEN Brain Science Institute
Tel: +81-(0)48-467-5971 / Fax: +81-(0)48-467-9670
Brain Science Research Planning Section
RIKEN Brain Science Institute
TELF048-467-9757@FAXF048-467-4914
Ms. Tomoko Ikawa (PI officer)
Global Relations Office
RIKEN
Tel: +81-(0)48-462-1225 / Fax: +81-(0)48-463-3687
Email: koho@riken.jp
References:
Moritz Helias, Moritz Deger, Stefan Rotter and Markus Diesmann. Instantaneous non-linear processing by pulse-coupled threshold units. PLoS Computational Biology (2010).

Hanuschkin A, Kunkel S, Helias M, Morrison A and Diesmann M (2010). A general and efficient method for incorporating precise spike times in globally time-driven simulations. Front. Neuroinform. 4:113. doi:10.3389/fninf.2010.00113

The simulation software is freely available from the NEST Initiative: http://www.nest-initiative.org

Journal information
PLoS Computational Biology

gro-pr | Research asia research news
Further information:
http://www.riken.jp
http://www.researchaustralia.org

More articles from Life Sciences:

nachricht Nanoparticle Exposure Can Awaken Dormant Viruses in the Lungs
16.01.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Cholera bacteria infect more effectively with a simple twist of shape
13.01.2017 | Princeton University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

Im Focus: Bacterial Pac Man molecule snaps at sugar

Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.

The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...

Im Focus: Newly proposed reference datasets improve weather satellite data quality

UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration

"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...

Im Focus: Repairing defects in fiber-reinforced plastics more efficiently

Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.

Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

Solar Collectors from Ultra-High Performance Concrete Combine Energy Efficiency and Aesthetics

16.01.2017 | Trade Fair News

3D scans for the automotive industry

16.01.2017 | Automotive Engineering

Nanoparticle Exposure Can Awaken Dormant Viruses in the Lungs

16.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>