The findings, which were discovered by researchers in Professor Claude Desplan’s and Steve Small’s laboratories in NYU’s Center for Developmental Genetics, offer new insight into the workings of developmental pathways across species. The study is published in the latest issue of the journal Science.
The researchers examined the fruit fly Drosophila and the wasp Nasonia as genetic model systems. Fruit flies’ development is well-understood by biologists and therefore serves as an appropriate focus for genetic analyses. In this study, the researchers sought to explore the generality of developmental mechanisms by comparing Drosophila with Nasonia, a distant species that diverged over 250 million years ago but one that presents many morphological similarities with flies in terms of development.
The research team’s results showed that flies and wasps employ most of the same genes and similar interactions among these genes, but some events are changed to adjust to the developmental constraints.
Flies rely on a gene called bicoid to pattern their early embryo. The bicoid gene product, a messenger RNA (mRNA), is localized at the anterior of the embryo where it is required both to promote anterior development and to repress posterior development. However, bicoid is unique to flies and does not exist in wasps or other species: The study’s findings show that it takes several mRNAs localized in the egg to achieve the same functions in wasps as bicoid does in flies. Two of these genes, which are found in most species of insects, are orthodenticle. Orthodenticle performs the anterior promoting function of bicoid while anterior localization of giant mRNA represses posterior development.
"This comparison of the molecular mechanisms employed by two independently evolved species not only uncovers those features essential to this portion of development, but also shows that we are now in a position to understand another species—in this case, the wasp—other than flies in the same depth," explained Desplan.
James Devitt | EurekAlert!
Scientists unlock ability to generate new sensory hair cells
22.02.2017 | Brigham and Women's Hospital
New insights into the information processing of motor neurons
22.02.2017 | Max Planck Florida Institute for Neuroscience
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
22.02.2017 | Power and Electrical Engineering
22.02.2017 | Life Sciences
22.02.2017 | Physics and Astronomy