Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Medicines from the rain forests

02.11.2006
A British drug discovery company which has developed the world's fastest drug profiling system has joined forces with a Brazilian company to seek new medicines from the South American rain forests.

At a time when the number of new drugs in the world's development pipeline has dwindled, the British company e-Therapeutics has formed a partnership with Brazilian company Grupo TCI to establish a joint research facility close to the Amazonian and Atlantic rain forests, to start testing substances from the millions of plants in the most diverse ecosystem on the planet.

New medicines are needed to combat a range of diseases which threaten to reach pandemic levels, including drug-resistant strains of tuberculosis and virus infections like avian flu. New drugs are also being sought for tropical diseases which occur in Brazil, such as hepatitis C, Chagas disease and Leishmaniasis.

In a separate deal, e-Therapeutics is joining forces with CURA, a pharmaceutical consortium backed by the Brazilian Government, which is establishing a cluster of drug discovery, development and marketing industries in North East Brazil. This will give e-Therapeutics a base from which to access to Brazilian pharmaceutical companies.

... more about:
»Brazilian »compound »e-Therapeutics »medicines

e-Therapeutics was spun out of Newcastle University in 2003 by Professor Malcolm Young, who developed new 'systems biology' techniques which can accurately predict the biological effect of any substance on any human tissue and on pathogens, such as bacteria and viruses. He attracted more than £10m research funding from the Engineering and Physical Sciences Research Council and other organisations to turn his ideas into practice.

Professor Young demonstrated the effectiveness of its technology by correctly predicting the effects of known drugs, such as 103 known antibiotics. But it also uncovered unknown antibiotics, which are now entering drug development.

e-Therapeutics is not alone in hunting for rain forest medicines but has the advantage of a system which typically takes only two weeks to assess a substance, as opposed to two years by conventional processes.

Professor Young, who is now Pro-Vice-Chancellor at Newcastle University, said: 'This is a fantastic opportunity to investigate Brazil's colossal biodiversity with our cutting edge technology. There is enormous potential for drug discovery in the rain forests, where there are millions of plant species, many of which produce bioactive chemicals.'

Roberto Marinho Filho, President of Grupo TCI, said: 'This new partnership will enable us to access our rich resource of natural compounds and, through e-Therapeutics novel technology, determine the medical use of these natural compounds. This will open the current bottlenecks in developing new drugs. We will be using the world’s fastest compound profiling system, so the process of discovery of medicines, which can reduce the two years required currently for these processes to about two weeks.'

e-Therapeutics was able to link up to the Brazilian companies with the assistance of the North East Process Industry Cluster (NEPIC), an organisation formed by the 200 Pharmaceutical, Biotechnology, Speciality, Commodity and Petrochemical companies based in the North East of England. NEPIC says that it intends to provide industrial connections and support for e-Therapeuitics as it grows. Funding for e-Therapeutics has included a £90,000 investment from NStar, an independent early stage technology venturing company, via its Proof of Concept Fund (POC) in 2004. This helped to accelerate the development of e-Therapeutics by financing research and demonstrating the company's capabilities in the pharmaceuticals and biotechnology markets.

Professor Malcolm Young | alfa
Further information:
http://www.ncl.ac.uk

Further reports about: Brazilian compound e-Therapeutics medicines

More articles from Life Sciences:

nachricht Decoding the genome's cryptic language
27.02.2017 | University of California - San Diego

nachricht New risk factors for anxiety disorders
24.02.2017 | Julius-Maximilians-Universität Würzburg

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Safe glide at total engine failure with ELA-inside

On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.

On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

New pop-up strategy inspired by cuts, not folds

27.02.2017 | Materials Sciences

Sandia uses confined nanoparticles to improve hydrogen storage materials performance

27.02.2017 | Interdisciplinary Research

Decoding the genome's cryptic language

27.02.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>