Chemical engineer Trude Tvete has found a bacteria-killing protein in plaice slime, isolated the protein from the slime and tested it on staphylococcus bacteria.
"The protein from fish slime has proven itself to be extremely deadly for the bacteria I have tested", says Trude Tvete, Nord-Trondelag University College (HiNT) in Norway.
Cleaned and tested slime
She has developed a technique to clean and separate the slime from plaice into its component parts and test it on several bacteria types.
"Previous research has shown that plaice slime kills bacteria, but it didn’t show which substance breaks the bacteria. I found that there is a protein in the slime that has the greatest effect,” says Trude Tvete.
Bacteria-killing substances from plants and animals are of interest for uses such as in hospitals that are beset with bacteria that has become resistant to antibiotics.
To make sure she had access to fresh plaice, she allied herself with local fishermen. In the laboratory, she scrapped the slime from the fish and testing with bacterial showed the slime with the greatest effect came from quite deep within the fish skin.
"So began the laborious work in the biotech laboratory to isolate the different substances from the fish slime. The protein we isolated was 95 percent pure in the end, and after that we tested it on the Staphylococcus aureus bacteria. It was shown to be very efficient at killing the bacteria", says Trude Tvete.
Could become medication
The bacteria-killing proteins and the other substances are an important part of the plaice’s immune system. One result of this research is that this slime can become the source for new medications for humans.
Because new infections constantly appear around the world as some bacteria become resistant to antibiotics, it is important to find new bacteria-killing agents. Substances from fish are especially interesting. The plaice has the potential to be fish farmed, and bio-products such as antibiotic agents could possibly increase the value of such an enterprise.
"Many bacteria-killing substances from mammals have been researched, but few have studied fish. The substances that can be isolated from fish have several properties that make them an attractive starting point for production of medications. They are built-up in a different way and can therefore overcome bacteria that have become resistant to antibiotics", explains Trude Tvete.
In the chemical engineering area at HiNT’s engineering department, research on the bacteria-killing properties of fish slime has been underway for several year. Several undergraduate chemical engineering students have worked with plaice slime as part of their major project.
Anne Sigrid Haugset | alfa
Researchers identify potentially druggable mutant p53 proteins that promote cancer growth
09.12.2016 | Cold Spring Harbor Laboratory
Plant-based substance boosts eyelash growth
09.12.2016 | Fraunhofer-Institut für Angewandte Polymerforschung IAP
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
09.12.2016 | Life Sciences
09.12.2016 | Ecology, The Environment and Conservation
09.12.2016 | Health and Medicine