Though linked to aging and cancer, reactive oxygen species plays another role
Reactive oxygen species (ROS) are normally produced as a product of metabolism, and, as their name implies, they are highly reactive with surrounding biological components. The ability of ROS to damage DNA and other critical molecules underlies their reputation for causing deleterious cellular effects and their association with aging, carcinogenesis, and atherosclerosis. However, in an unanticipated discovery suggesting that ROS may play important positive roles in development, researchers have found that the production of ROS by a particular enzyme is essential for inner ear development and for the ability to properly maintain balance.
The work is reported in Current Biology by a team of researchers, including Peter Kiss and Botond Banfi of the University of Iowa.
A biologically constructive function for ROS in development was unanticipated. Even a previously known beneficial role for ROS seems to be intimately linked to toxicity: White blood cells generate ROS by an NADPH oxidase enzyme to kill invading bacteria. In recent years, evidence has been accumulating that other NADPH oxidases, similar to that of white blood cells, are widespread in the body, but their function remains largely obscure.
Heidi Hardman | EurekAlert!
CRISPR meets single-cell sequencing in new screening method
19.01.2017 | CeMM Forschungszentrum für Molekulare Medizin der Österreichischen Akademie der Wissenschaften
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An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
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Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
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19.01.2017 | Studies and Analyses