Weizmann Institute scientists develop new analytical method
Some fundamental outstanding questions in science – "Where do stem cells originate?" "How does cancer develop?" "When do cell types split off from each other in the embryo?" – might be answered if scientists had a way to map the history of the body’s cells going back to the fertilized egg. Now, a multidisciplinary team at the Weizmann Institute of Science has developed an analytical method that can trace the lineage trees of cells.
This accomplishment started with a challenge to common wisdom, which says that every cell in an organism carries an exact duplicate of its genome. Although mistakes in copying, which are passed on to the next generation of cells as mutations, occur when cells divide, such tiny flaws in the genome are thought to be trivial and mainly irrelevant. But research students Dan Frumkin and Adam Wasserstrom of the Institute’s Biological Chemistry Department, working under the guidance of Prof. Ehud Shapiro of the Biological Chemistry and Computer Science and Applied Mathematics Departments, raised a new possibility: though biologically insignificant, the accumulated mutations might hold a record of the history of cell divisions. These findings were published today in PLoS Computational Biology.
Elizabeth McCrocklin | EurekAlert!
Closing the carbon loop
08.12.2016 | University of Pittsburgh
Newly discovered bacteria-binding protein in the intestine
08.12.2016 | University of Gothenburg
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
08.12.2016 | Life Sciences
08.12.2016 | Physics and Astronomy
08.12.2016 | Materials Sciences