Researchers know that the many different roads to cell suicide all run through mitochondria, but do not know which roads are the ones most traveled by the signals that signify death
The story of how mitochondria are recruited during times of stress to choreograph apoptosis--the cells dance of death--is a story that fails to tell which particular set of steps the cells use most often, according to investigators at St. Jude Childrens Research Hospital and the La Jolla Institute of Allergy and Immunology (San Diego, CA).
Mitochondria are sacs of enzymes in the cell that extract energy from food and store this energy in the high-powered chemical bonds of molecules called ATP. Virtually all activity of cells requires energy supplied by ATP, which acts as the "currency" with which the cell "buys" chemical reactions.
The fact that more than 100,000 research papers on apoptosis have been published is ironic, since this vast amount of information contributes to the confusion over which signaling pathways are most important for triggering this process, according to Douglas R. Green, Ph.D., chair of Immunology at St. Jude and holder of the Peter C. Doherty Endowed Chair of Immunology. Green is senior author of an editorial on apoptosis that appears in the October 7 issue of Science.
Carrie Strehlau | EurekAlert!
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More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
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The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
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