Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Tuberculosis infection prevention by quick testing

28.09.2005


With a new DNA test, tuberculosis infection can be revealed so quickly that a patient doesn’t have time to infect others. This can be an important key to effective control of the disease.



The Norwegian biotechnology firm Genpoint is running trials, along with others financed by the Norwegian Research Council’s biotechnology program, of new and effective DNA tests at Ullevål University Hospital, the country’s national laboratory for tuberculosis.

Norwegian health officials calculate that a person infected with tuberculosis, with today’s diagnosis methods, can infect on average 20 others before the disease is detected and the patient can be isolated and treated.


The current manual test methods take at least a week, and the bacteria must incubate for up to eight weeks before an precise diagnosis can be made. This is a comprehensive process for both the patient and the laboratories that perform the tests. In addition, the tests must often be taken several times over a period of up to six months before it is certain what type of tuberculosis bacteria is being dealt with.

Genpoint’s automated DNA method simplifies diagnostics and provides test results that are available in a few minutes at best and in a few hours at worst. Therefore health personnel are able to test much larger groups, gaining much better and more effective control of the disease and its transmission.

The test methods are approved in the sense that Genpoint is in the process of fulfilling the requirements for documentation that have been set by the hospital laboratory in close co-operation with experts in the hospital milieu.

-We expect to be finished with the documentation period late this autumn and that the tests in the best case can be available for ordinary use in the country’s laboratories from late autumn or early next year, explains Genpoint’s Administrative Director Geir Gogstad.

The new test methods will mean an enormous difference from the existing test when it comes to the authorities’ ability to treat tuberculosis patients.

-Many more can be tested using far less money than today, without an increase of personnel in the health care sector”, says Gogstad.

Magic spheres

Genpoint makes use of magic spheres to isolate bacteria and holds a world-wide patent for the process. The spheres pull bacteria to themselves, and then dissolve the bacteria so that the DNA is released and absorbed by the spheres. With further analysis of the DNA, the bacteria can be identified. Both the cells and the DNA are captured by the same sphere surface, making it much easier to automate the process.

Genpoint operates in the global market with its products. New forms of tuberculosis bacteria are constantly being discovered, or so called mycobacteria, which tuberculosis-related bacteria. Many of these are resistant to antibiotics. Therefore the job to find more effective and speedy methods to identify the disease and reduce infection are more important than ever before, even though the disease over the last 40 years has been held in check in northern Europe thanks to vaccination programmes.

In the next round, Genpoint plans to further develop its tests to include multi-resistant staphylococcus, which is a world-wide problem in hospitals, but has begun to manifest itself as a contagion outside of hospitals. In this case, a quick and reliable method for identifying the oganism and beginning treatment is even more crucial because the staphylococcus is very resistant to antibiotics.

Elisabeth Kirkeng Andersen | alfa
Further information:
http://www.genpoint.no

More articles from Life Sciences:

nachricht Multi-institutional collaboration uncovers how molecular machines assemble
02.12.2016 | Salk Institute

nachricht Fertilized egg cells trigger and monitor loss of sperm’s epigenetic memory
02.12.2016 | IMBA - Institut für Molekulare Biotechnologie der Österreichischen Akademie der Wissenschaften GmbH

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

Im Focus: Fraunhofer ISE Develops Highly Compact, High Frequency DC/DC Converter for Aviation

The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.

Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

UTSA study describes new minimally invasive device to treat cancer and other illnesses

02.12.2016 | Medical Engineering

Plasma-zapping process could yield trans fat-free soybean oil product

02.12.2016 | Agricultural and Forestry Science

What do Netflix, Google and planetary systems have in common?

02.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>