Researchers at Case Western Reserve University School of Medicine and the Ireland Cancer Center of University Hospitals of Cleveland report identifying a new DNA gene marker, vimentin, that was shown in a recent study to be three times more effective in detecting colon cancer than the standard doctors office test that detects blood in the stool. The study, appearing in the August 3, 2005 issue of the Journal of the National Cancer Institute, was conducted by a team also comprised of researchers with the Howard Hughes Medical Institute and from the Massachusetts biotechnology company, EXACT Sciences Corporation.
Through use of this single vimentin marker, the researchers were able to detect colon cancer in 46 percent of patients studied, compared with 15 percent for the standard fecal occult blood test. The vimentin marker was also very effective in detecting colon cancer in the early stages of development, when the disease is most curable.
The researchers targeted a gene called vimentin that usually does not play a role in normal colon cells, but serves as a marker for the development of colorectal cancer. The analysis, which was performed using vimentin alone and no other markers in the panel, relied on DNA extracted from stool samples of the participating patients. The analysis detected cancers in 43 of 94 patients (46 percent), and detected early stages of cancer in 26 out of 60 cases, or 43 percent of the time.
George Stamatis | EurekAlert!
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Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
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In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
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By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
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COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
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'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
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