Multiple strains of the flu virus, circulating in a population at the same time, can reshuffle their genes and create a new virus, one capable of infecting many more people, according to a new study in the open-access journal PLoS Biology. This finding may help scientists make better predictions about which viral strains will attack during upcoming flu seasons and design more effective flu vaccines.
In the first large-scale effort to sequence the flu genome, Edward Holmes, David Lipman, and colleagues examined the genomes of 156 influenza A viruses (serotype H3N2) collected by New York State public health officials between 1999 and 2004. "We found that there are co-circulating minor variants that are not infecting many people," says Lipman. "One of these can become the next epidemic strain."
These co-circulating viruses can exchange genes in a way that creates novel, epidemiologically significant strains--a process that can occur when someone is infected simultaneously by more than one strain. The genetic reshuffling demonstrated in this study is the first to examine in detail a reassortment event from a persistently cocirculating minor strain to a previously dominant strain leading to an epidemiologically significant outcome--the emergence of the "Fujian" strain in the 2003-2004 flu season.
Paul Ocampo | EurekAlert!
Atomic Design by Water
23.02.2018 | Max-Planck-Institut für Eisenforschung GmbH
22.02.2018 | Albert-Ludwigs-Universität Freiburg im Breisgau
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
22.02.2018 | Life Sciences
22.02.2018 | Physics and Astronomy
22.02.2018 | Earth Sciences