Coming full circle has new meaning for researchers who demonstrated a promising new approach integrating scientific experimentation and mathematical modeling to study a key signaling pathway that helps cells decide whether to grow or die.
With implications for disease characterization, biotechnology and drug design, the approach tested by researchers at the Medical University of South Carolina (MUSC) and the Georgia Institute of Technology offers an efficient way of gaining useful knowledge from the massive amounts of complex biological information generated with todays advanced analysis technology.
The work represents another step toward modeling complex biological systems accurately enough to make useful predictions. "Our research went beyond describing a one-way street," said Professor Eberhard Voit of the Georgia Tech/Emory University Wallace H. Coulter Department of Biomedical Engineering. "Experimenters generate data, modelers design a mathematical model that fits the data, and often thats the end of the story. But, in this research, the experimenters actually tested hypotheses generated by the model, thus closing the circle."
Jane Sanders | EurekAlert!
New technology offers fast peptide synthesis
28.02.2017 | Massachusetts Institute of Technology
Biofuel produced by microalgae
28.02.2017 | Tokyo Institute of Technology
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
28.02.2017 | Life Sciences
28.02.2017 | Power and Electrical Engineering
28.02.2017 | Information Technology