Understanding how muscle cells form is crucial to developing new treatments for diseases such as muscular dystrophy and to treating muscle injuries. However, while scientists have focused on muscle cells in culture, they know little about how muscle cells form in a developing embryo.
In this months issue of the journal Developmental Cell, Clarissa Henry, assistant professor in the University of Maine Dept. of Biological Sciences, reports findings from a study of muscle cell development in zebrafish embryos. Looking at the formation of two types of muscle fibers, Henry and co-author Sharon L. Amacher of the University of California, Berkeley, describe a process regulated by a gene known as Hedgehog.
The article is titled "Zebrafish Slow Muscle Cell Migration Induces a Wave of Fast Muscle Morphogenesis." It is based on research at the University of California, Berkeley where Henry was a post-doctoral scientist before coming to UMaine.
Nick Houtman | EurekAlert!
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