At the 2004 ASCB Meeting: Visualizing the Kiss of Death
The very idea threw the Victorian poet Alfred Lord Tennyson into a funk. “Nature, red in tooth and claw,” Tennyson called the nightmarish idea that life was an unending battle to eat or be eaten. If only Tennyson could have seen the latest self-defense videos made by Daniela Malide and others at the National Institutes of Health in Bethesda, MD. Using time-lapse confocal laser scanning microscopy, Malide captured human T-cells picking up distress signals from cells infected with a virus and zeroing in for the kill.
Scientists have worked out experimentally many of the mechanisms and tactics of the immuno-surveillance system but Malide’s real-time videos show the action as it unfolds. The videos also revealed for the first time that “killer” T-cells take far longer to dispatch their viral enemies than was generally believed. Instead of a brisk 10-minute rubout, these killer T-cells can take up to two hours to mount a fatal assault.
Molecular Force Sensors
20.09.2017 | Max-Planck-Institut für Biochemie
Foster tadpoles trigger parental instinct in poison frogs
20.09.2017 | Veterinärmedizinische Universität Wien
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...
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20.09.2017 | Physics and Astronomy