Decreasing testosterone boosts immunity because testosterone helps control T-lymphocytes, the attack cells of the immune system, according to Mayo Clinic-led research in laboratory animals. The findings appear in the Nov. 15 edition of the Journal of Immunology.
Collaborators include scientists from Roswell Park Cancer Institute, Buffalo, N.Y.; the Tumor Immunity and Tolerance Section of the Laboratory of Molecular Immunoregulation, National Cancer Institute; and Howard Hughes Medical Institute/Memorial Sloan-Kettering Cancer Center. "What we are showing is that testosterone seems to impede immunity," says Eugene Kwon, M.D., the Mayo Clinic urologist and immunology researcher who led the research team. "However, when testosterone is withdrawn, you get an increased host immune response indicated by the rising numbers of immune cells that are available to participate."
T-lymphocytes are cells that are vital to controlling the bodys immune response. "T cells," as they are usually called by scientists, are white blood cells that can fight against tumor cells and infection. Alternatively, T cells can help other immune cells known as "B cells" make antibodies to defend the body against certain bacterial and fungal infections, and possibly against cancer. The research findings may have broad potential applications to public health. For example, knowing that testosterone levels affect T-cell response may help:
Significance of the Research
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22.09.2017 | Max-Planck-Institut für Biochemie
Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.
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For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
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