New research from the University of North Carolina at Chapel Hill has identified a cellular enzyme that helps regulate the synthesis of proteins essential to cell functioning throughout the life of the organism. The enzyme binds to histone messenger RNA, which is DNAs blueprint for histone protein synthesis.
As histones represent about half of the nucleoprotein complex known as chromatin, they are vital to DNA replication and the subsequent assembly of chromosomes A report of the research appears in the Aug. 29 edition of the science journal Molecular Cell.
"This is the first enzyme Im aware of thats specific for a particular group of messenger RNAs," said Dr. William F. Marzluff, professor of biochemistry and biophysics at UNCs School of Medicine.
Leslie Lang | idw
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