New research dismisses a widely held assumption about how cells grow
Research published today in Journal of Biology challenges an assumption about cell growth that underpins modern cellular biology. Ian Conlon and Martin Raff, of University College London, show that mammalian cells do not regulate their size in the way scientists have assumed they do since the 1970s.
Conlon and Raff conducted a series of experiments, using Schwann cells from the sciatic nerve of rats, to establish how mammalian cells control their size and ‘decide’ when to divide. This processes of cell size, growth and division has been widely studied in yeast for thirty years, and many aspects are the same in the two types of cell. Both yeast and mammalian cells are known to be able to maintain a constant average size as they grow and divide. It has therefore been assumed that the ‘checkpoints’ yeast cells use to ensure that they divide when they reach the correct size are mirrored by checkpoints in mammalian cells, but that assumption had not been tested experimentally - until now.
Using precise measurements, Conlon and Raff found key differences in the ways yeast and mammalian cells grow. Yeast cells grow exponentially, doubling in size over a fixed time period, but mammalian cells grow in a linear way, getting larger by the same amount each day; this means that the rate at which mammalian cells grow is the same regardless of the cell’s size, whereas in yeast big cells grow faster than small ones.
Grace Baynes | BioMed Central Limited
The dense vessel network regulates formation of thrombocytes in the bone marrow
25.07.2017 | Rudolf-Virchow-Zentrum für Experimentelle Biomedizin der Universität Würzburg
Fungi that evolved to eat wood offer new biomass conversion tool
25.07.2017 | University of Massachusetts at Amherst
Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers
Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...
Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.
At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...
3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects
A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...
Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.
For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...
What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.
To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...
21.07.2017 | Event News
19.07.2017 | Event News
12.07.2017 | Event News
25.07.2017 | Physics and Astronomy
25.07.2017 | Earth Sciences
25.07.2017 | Life Sciences