In the latest January 10th issue of Cell, a discovery is published by Barends et al. of Leiden University about the artful way by which an infecting plant virus succeeds in conquering the protein factories (ribosomes) of a host cell for subsequent enforced production of viral proteins. To this aim, the virus uses a molecular ’Trojan Horse’ mimicking the shape of transfer RNA, the regular molecular ’van’ for the delivery of amino acids as protein building-stones into those factories.
In the case of Turnip Yellow Mosaic Virus, the transfer-RNA mimic appears to have also smuggled the complete viral RNA in its cargo, with a coercive programme for the production of the viral replicase enzyme. As a result of the replicase action, many new copies of virus RNA are generated in the interior of the host cell for subsequent production of a load of new virus particles. Also other RNA viruses might deploy a comparable ’Trojan Horse’ in their molecular ’struggle for life’.
From a philosophical point this novel mechanism may also inspire to further image forming about the molecular evolution of ribosomal protein synthesis at the genesis of primordial life from an RNA world.
Dr. Barend Kraal | alfa
Gene therapy shows promise for treating Niemann-Pick disease type C1
27.10.2016 | NIH/National Human Genome Research Institute
'Neighbor maps' reveal the genome's 3-D shape
27.10.2016 | International School of Advanced Studies (SISSA)
Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.
This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
27.10.2016 | Materials Sciences
27.10.2016 | Physics and Astronomy
27.10.2016 | Life Sciences