Berlin researchers can explain how local information is stored and transported in the brain
This morning, shortly after waking up: did I first go to the bathroom and then turned on the coffee machine in the kitchen—or vice versa? Sometimes you are uncertain whether you have followed an everyday routine as usual or not.
Jorge Jaramillo, first author of the study
Jorge Jaramillo, 2014
The brain has a certain mechanism of storing sequences of spatial events. Part of this mechanism can now be explained by a reasearch team headed by Professor Richard Kempter at the Bernstein Center Berlin and the Humboldt-Universität in Berlin.
The study, entitled: "Modeling Inheritance of phase precession in the hippocampal formation", has been published in The Journal of Neuroscience. Using a computer model, the scientists are able to predict how some nerve cells may stimulate specific neurons in other brain regions to fire in a specific rhythm.
To analyze how the rhythm comes about, the researchers simulated the behavior of nerve cells in the diverse brain regions on the computer. The result of their model: the rhythm may be passed on from one region to the next and does not need to emerge individually in the respective areas.
"Spatial sequences, such as walking routes, are processed in the hippocampus," says Jorge Jaramillo, first author of the study. The hippocampus is a structure in the mammalian brain, which is crucial for the explicit memory (facts, events, sequences). Here are neurons, which are responsible for the so-called "place field": They fire when we find ourselves at a particular point in space.
"If we measure the entire brain activity using EEG (electroencephalography), you see very typical activity oscillations in the hippocampus, the so-called theta rhythm." Nerve cells that are in the process of encoding spatial information start to fire offset in time to this rhythm. This process creates a complex spatial-temporal pattern of electrical brain activity in the brain, which has an important role in the storage of spatial information. The phase-shifted rhythm has been observed in different subregions of the hippocampus – until now it had been unclear how it arises in the individual areas.
"Ultimately, it allows us to better understand other aspects of memory too, not only spatial, as the basic principles are similar," says Jaramillo.
The Bernstein Center Berlin is part of the National Bernstein Network Computational Neuroscience in Germany. With this funding initiative, the German Federal Ministry of Education and Research (BMBF) has supported the new discipline of Computational Neuroscience since 2004 with over 180 million Euros. The network is named after the German physiologist Julius Bernstein (1835-1917).
Prof. Dr. Richard Kempter
Department of Biology
Institute for Theoretical Biology (ITB)
Humboldt-Universität zu Berlin
Philippstr. 13, Building number 4 (Ostertaghaus)
Tel: +49 (0)30-2093-98404
J. Jaramillo, R. Schmidt, R. Kempter (2014): Modeling Inheritance of Phase Precession in the Hippocampal Formation. The Journal of Neuroscience, 34(22): 7715 – 7731.
The first genome of a coral reef fish
29.09.2016 | King Abdullah University of Science and Technology
New switch decides between genome repair and death of cells
27.09.2016 | University of Cologne - Universität zu Köln
Friction stir welding is a still-young and thus often unfamiliar pressure welding process for joining flat components and semi-finished components made of light metals.
Scientists at the University of Stuttgart have now developed two new process variants that will considerably expand the areas of application for friction stir welding.
Technologie-Lizenz-Büro (TLB) GmbH supports the University of Stuttgart in patenting and marketing its innovations.
Friction stir welding is a still-young and thus often unfamiliar pressure welding process for joining flat components and semi-finished components made of...
Optical quantum computers can revolutionize computer technology. A team of researchers led by scientists from Münster University and KIT now succeeded in putting a quantum optical experimental set-up onto a chip. In doing so, they have met one of the requirements for making it possible to use photonic circuits for optical quantum computers.
Optical quantum computers are what people are pinning their hopes on for tomorrow’s computer technology – whether for tap-proof data encryption, ultrafast...
The Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP has been developing various applications for OLED microdisplays based on organic semiconductors. By integrating the capabilities of an image sensor directly into the microdisplay, eye movements can be recorded by the smart glasses and utilized for guidance and control functions, as one example. The new design will be debuted at Augmented World Expo Europe (AWE) in Berlin at Booth B25, October 18th – 19th.
“Augmented-reality” and “wearables” have become terms we encounter almost daily. Both can make daily life a little simpler and provide valuable assistance for...
With the help of artificial intelligence, chemists from the University of Basel in Switzerland have computed the characteristics of about two million crystals made up of four chemical elements. The researchers were able to identify 90 previously unknown thermodynamically stable crystals that can be regarded as new materials. They report on their findings in the scientific journal Physical Review Letters.
Elpasolite is a glassy, transparent, shiny and soft mineral with a cubic crystal structure. First discovered in El Paso County (Colorado, USA), it can also be...
For the first time, Fraunhofer IKTS shows additively manufactured hardmetal tools at WorldPM 2016 in Hamburg. Mechanical, chemical as well as a high heat resistance and extreme hardness are required from tools that are used in mechanical and automotive engineering or in plastics and building materials industry. Researchers at the Fraunhofer Institute for Ceramic Technologies and Systems IKTS in Dresden managed the production of complex hardmetal tools via 3D printing in a quality that are in no way inferior to conventionally produced high-performance tools.
Fraunhofer IKTS counts decades of proven expertise in the development of hardmetals. To date, reliable cutting, drilling, pressing and stamping tools made of...
29.09.2016 | Event News
28.09.2016 | Event News
27.09.2016 | Event News
29.09.2016 | Materials Sciences
29.09.2016 | Materials Sciences
29.09.2016 | Interdisciplinary Research