A red-haired Duroc pig from a farm at the University of Illinois will now be among the growing list of domesticated animals that have had their genomes sequenced. Researchers will announce the achievement Monday (Nov. 2) at a meeting at the Wellcome Trust Sanger Institute, Hinxton, U.K.
“The pig is a unique animal that is important for food and that is used as an animal model for human disease,” said Larry Schook, a University of Illinois professor of biomedical sciences and leader of the sequencing project. “And because the native wild animals are still in existence, it is a really exciting animal to look at to learn about the genomic effects of domestication,” he said.The Duroc is one of five major breeds used in pork production around the world and is one of about 200 breeds of domesticated pigs. There are also numerous varieties of wild boar, the non-domesticated pigs that are believed to have originated in Eurasia.
The effort cost about $24.3 million, with additional support from the USDA Agricultural Research Service and many other American, Asian and European funders. (See below for a complete list). Another requirement of participation was that the findings be made public, with no proprietary interests allowed.
The draft sequence, which is about 98 percent complete, will allow researchers to pinpoint genes that are useful to pork production or are involved in immunity or other important physiological processes in the pig. It will enhance breeding practices, offer insight into diseases that afflict pigs (and, sometimes, also humans) and will assist in efforts to preserve the global heritage of rare, endangered and wild pigs. It also will be important for the study of human health because pigs are very similar to humans in their physiology, behavior and nutritional needs.
“We are excited to have the swine genome sequence and anticipate this will accelerate the rate of genetic improvement in swine as the bovine sequence is impacting the dairy industry’s genetic gains,” said Steve Kappes, deputy administrator of Animal Production and Protection for the USDA Agricultural Research Service.
“This is a great day for the pig research community,” said professor Alan Archibald, of the Roslin Institute and R(D)SVS at the University of Edinburgh. “When we launched the international pig gene mapping project almost 20 years ago, few if any of us thought a pig genome sequence was attainable or affordable.”
The pig genome sequence is an essential first tool that will allow scientists to delve into the health, science and natural history of the pig, Schook said.
"This is just the end of the beginning of the process,” he said. “Now we’re just beginning to be able to answer a lot of questions about the pig.”
“We are delighted to have contributed to this important collaboration,” said professor Allan Bradley, director of the Wellcome Trust Sanger Institute, which performed most of the sequencing. “This sequence provides a tool of real value in helping the research community to better understand human diseases, in particular by facilitating cardiovascular, pulmonary, gastrointestinal and immunological studies. Thanks to the immediate release of sequence data as it has been produced, the scientific impact of this research is already being felt.”
In addition to the USDA funding, funding and technical support were provided by the Agence Nationale de la Recherche; European Union SABRE; the Institute for Pig Genetics, Netherlands; INRA Genescope, France; Iowa Pork Producers Association; Iowa State University; Korean National Livestock Research Institute; National Institute of Agrobiological Sciences, Japan; National Pork Board, U.S.; North Carolina Pork Council; North Carolina Agricultural Research Service; North Carolina State University; University of Illinois; the UK-based Wellcome Trust Sanger Institute; the Roslin Institute, University of Edinburgh; University of Illinois Livestock Genome Sequencing Initiative; and the UK-based Biotechnology and Biological Sciences Research Council.
Diana Yates | University of Illinois
At last, butterflies get a bigger, better evolutionary tree
16.02.2018 | Florida Museum of Natural History
New treatment strategies for chronic kidney disease from the animal kingdom
16.02.2018 | Veterinärmedizinische Universität Wien
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).
Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
16.02.2018 | Information Technology
16.02.2018 | Health and Medicine
16.02.2018 | Physics and Astronomy