As a part of emergency government research aimed at addressing this need, RIKEN and University of Tokyo, are developing an H1N1 detection technique based on its SmartAmp technology.
With the number of novel influenza A (H1N1) cases increasing in countries around the world, the rapid spread of the virus has triggered worldwide alarm. There is a pressing need at medical institutions for methods to detect whether individuals are infected with the virus in order to effectively slow its spread.
As a part of emergency government research aimed at addressing this need, the RIKEN Omics Science Center (OSC), in cooperation with the Institute of Medical Science at the University of Tokyo, is developing an H1N1 detection technique based on its SmartAmp technology.
The SmartAmp (Smart Amplification Process) reduces the single nucleotide polymorphism (SNP) analysis time to just half an hour, and the precise results thus produced allow genetic diagnosis to be carried out immediately upon initial consultation. Using this technology, OSC has developed methods for detecting the regular seasonal influenza A virus, the H3N2 virus, and the susceptibility of these viruses to Tamiflu treatment. Most laboratories continue to use the RT-PCR system, which for H1N1 necessitates reverse transcription in order to convert RNA into DNA (H1N1 is an RNA virus). The SmartAmp approach carries out this step in parallel with DNA amplification. The time and effort required for the new technique is thus roughly the same as in the conventional SmartAmp process.
OSC researchers are currently applying SmartAmp for diagnosis of the H1N1 virus, as well as developing reagents for virus detection and optimizing the conditions for the reagents. Once optimization is complete, tests will be performed on actual samples from patients at the Osaka Prefectural Institute of Public Health. In cooperation with the Infectious Disease Surveillance Center and the International Medical Center of Japan, the goal is to deploy the technique to clinics within the next six months.
BigH1 -- The key histone for male fertility
14.12.2017 | Institute for Research in Biomedicine (IRB Barcelona)
Guardians of the Gate
14.12.2017 | Max-Planck-Institut für Biochemie
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
14.12.2017 | Health and Medicine
14.12.2017 | Physics and Astronomy
14.12.2017 | Life Sciences