Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Analyzing the Sheep Genome for Parasite Resistance

19.10.2011
Genetic resistance to a parasitic nematode that infects sheep has been discovered by a team of scientists with the U.S. Department of Agriculture (USDA) and the International Livestock Research Institute (ILRI).

The researchers are the first to detect quantitative trait loci (QTL), genetic locations on chromosomes, for resistance to gastrointestinal nematode parasites in a double-backcross population derived from African native sheep.

The parasites, common in tropical regions, cause significant economic and production losses in Africa each year. Sheep infected with parasites suffer from diarrhea, anemia, weight loss and sometimes death.

Geneticist Tad Sonstegard at the Agricultural Research Service (ARS) Henry A. Wallace Beltsville Agricultural Research Center in Beltsville, Md., and researchers at ILRI in Kenya hope to identify genes that increase tolerance to parasites and improve production of grazing animals. ARS is USDA's chief intramural scientific research agency, and this research supports USDA's priority of promoting international food security.

In one study, researchers mapped the regions of the genome that control resistance to gastrointestinal nematode parasites in a sheep population bred by ILRI. Hybrid rams were produced by mating a Red Maasai, which is tolerant to gastrointestinal parasites, to a Dorper, a breed that is more susceptible to the parasite. Several of the hybrid ram offspring were then bred to either Red Maasai or Dorper ewes to complete the backcross.

Scientists genotyped 20 percent of the backcross progeny to map QTL that affect parasite-resistance traits. Blood packed-cell volume and fecal egg count-indicators of parasites-were collected for three months from more than 1,060 lambs that grazed on parasite-infected pastures. Scientists selected lambs for genotyping based on parasite indicators. They detected significant QTL for average fecal egg count and packed-cell volume on chromosomes 3, 6, 14, and 22.

Future studies will focus on genotyping the same animals using the OvineSNP50, according to Sonstegard. The OvineSNP50 is a powerful tool that can examine more than 50,000 locations in the genome.

Findings from this research were published online in Animal Genetics in May 2011.

Read more about this research in the October 2011 issue of Agricultural Research magazine

Sandra Avant | EurekAlert!
Further information:
http://www.ars.usda.gov

More articles from Life Sciences:

nachricht Flow of cerebrospinal fluid regulates neural stem cell division
22.05.2018 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Chemists at FAU successfully demonstrate imine hydrogenation with inexpensive main group metal
22.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

Im Focus: Computer-Designed Customized Regenerative Heart Valves

Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.

Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...

Im Focus: Light-induced superconductivity under high pressure

A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.

Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Supersonic waves may help electronics beat the heat

18.05.2018 | Power and Electrical Engineering

Keeping a Close Eye on Ice Loss

18.05.2018 | Information Technology

CrowdWater: An App for Flood Research

18.05.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>