The software may be freely downloaded at www.copasi.org for non-commercial purposes.
Pedro Mendes, Associate Professor at VBI, remarked: “The first official release of COPASI represents a key milestone in delivering a fully comprehensive software solution for modeling and simulation to the life science community.” He added: “We have been working closely with Ursula Kummer’s group at EML Research to deliver an open-source software package that aids in the understanding of cellular and molecular behavior and which facilitates the quantitative interpretation of modern experiments. COPASI is the culmination of six years of intense development work to deliver a package that meets the real needs of life scientists. The future development of COPASI will continue to strive towards providing a powerful package that every biologist can use, not just experts in systems biology.”
COPASI simplifies the task of model building by assisting the user in translating the language of chemistry (reactions) to mathematics (matrices and differential equations). The user-friendly interface is combined with a set of sophisticated numerical algorithms that assure the results are obtained quickly and accurately. COPASI simulates the kinetics of systems of biochemical reactions and provides a number of tools to fit models to data, optimize any function of the model, perform metabolic control analysis and linear stability analysis.
Dr. Ursula Kummer, Principal Investigator at EML Research, commented: “Simulation and modeling are becoming increasingly important tools in systems biology research and can be used to test the physical and chemical limitations as well as feasibility of a wide range of biochemical reactions. We anticipate that COPASI will prove invaluable to researchers not only in simulating increasingly complex networks but also in helping to understand how external factors, for example drugs, impact metabolic systems.” She added: “We have already seen many applications from our existing user community and expect many more due to COPASI’s inherent flexibility for top-down and bottom-up modeling.”
Information integration and artificial intelligence for better diagnosis and therapy decisions
24.05.2017 | Fraunhofer MEVIS - Institut für Bildgestützte Medizin
World's thinnest hologram paves path to new 3-D world
18.05.2017 | RMIT University
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy