“The new community associated MRSA strains appear to be more virulent and more easily spread between people”, says Dr Marina Morgan from the Royal Devon & Exeter Foundation NHS Trust. “These community associated versions have been found in people with few, if any, reasons to have MRSA. Typically they haven’t recently been in hospital, or and are not looking after or living with people with MRSA.”
Although more antibiotics are still effective against community MRSA than against the hospital MRSA, the community associated infections are often more virulent. Most can also produce a toxin called Panton-Valentine leucocidin, or PVL, that kills white blood cells – our bodies’ key defence against invasive bacteria.
“Although the resistant strain is not yet widespread in the UK, we have seen increasing numbers of PVL- toxin producing Staphylococcus aureus infections, mainly presenting with recurrent boils and abscesses. This excessive production of white cells to compensate for those killed by the PVL toxin leads to recurrent severe boils and abscesses. The MRSA is easily spread by close contact, such as in families, nurseries and athletic teams”, says Dr Morgan. “These new strains of bacteria appear to be able to stick to damaged skin and airways better than hospital MRSA strains, and they also multiply at a faster rate.
A minority of patients carrying these PVL-producing staphylococci can suffer severe invasive infections such as septicaemia or a lethal form of pneumonia where the lung tissue itself is destroyed by the toxins. With this type of necrotising PVL pneumonia, even with the strongest antibiotics, more than 60% of otherwise healthy young and fit people will die”.
So far community associated MRSA strains are mainly spreading in America, where they are a major cause of infection in children. Whilst doctors do not know if the bacteria could spread as rapidly in the UK, they are already worried. These new strains of bacteria appear to be able to stick to damaged skin and airways better than hospital MRSA strains, and they also multiply at a faster rate.
“These infections are easily missed clinically, where they can be dismissed as just recurrent boils and overlooked until a serious infection develops”, says Dr Morgan. “Then, with severe invasive infections like pneumonia, early diagnosis is vital as treatment with the correct antibiotics and massive doses of immunoglobulin can save children’s lives”.
If the community associated MRSA strains take hold and spread in the UK as they have in the USA then many more patients with unsuspected MRSA will be admitted to hospitals, given the wrong antibiotics, and when doctors finally realise the infection is MRSA, by the time patients get the correct treatment it may be too late.
ICTM Conference 2017: Production technology for turbomachine manufacturing of the future
16.11.2016 | Fraunhofer-Institut für Produktionstechnologie IPT
Innovation Day Laser Technology – Laser Additive Manufacturing
01.11.2016 | Laser Zentrum Hannover e.V.
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
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