Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cancer Research Award to Johns Hopkins Basic Scientist

27.04.2010
Joshua T. Mendell, M.D., Ph.D., an associate professor in the McKusick-Nathans Institute of Genetic Medicine at the Johns Hopkins University School of Medicine, and a Howard Hughes Medical Institute Early Career Scientist, is the recipient of the 30th annual American Association for Cancer Research Award for Outstanding Achievement in Cancer Research. The award is for his work to advance the understanding of microRNAs (miRNAs), genetic signaling elements involved in gene “silencing,” which are important for normal physiology and diseases such as cancer.

The award, which comes with a $5,000 cash prize, was presented during the 101st annual meeting of the American Association for Cancer Research, at which Mendell delivered a lecture, “MicroRNA Reprogramming in Cancer: Mechanisms and Therapeutic Opportunities.” His recent research demonstrates that the delivery of microRNAs to cancer cells represents a promising strategy for cancer therapy.

“To be included among the incredible past recipients of this award — many of whom I view as scientific role models — is truly humbling and very exciting,” Mendell says. “This recognition suggests that our work has addressed important scientific questions that have had a broad impact on the cancer research community, and provides inspiration to continue to investigate fundamental questions in cancer biology.”

Mendell’s research focuses on short pieces of RNA that do not encode protein but control genes. These small molecules can act as either cancer-driving oncogenes or as tumor-suppressor genes, which prevent cells from becoming cancerous. Mendell’s laboratory is studying microRNAs in human cells and in animals such as zebrafish and mice to understand how aberrant miRNA activity contributes to cancer and to develop miRNA-based therapeutic strategies.

Mendell earned both his medical degree (2003) and a Ph.D. (2001) at Johns Hopkins before starting his lab there. He has received a number of awards and recognitions, including being named the Outstanding Young Scientist in the State of Maryland (Allan C. Davis Medal), 2007; a “Top Young Investigator of 2007” by Genome Technology Magazine, 2007; a Leukemia and Lymphoma Society Scholar, 2008; and a Howard Hughes Medical Institute Early Career Scientist, 2009.

“We are proud that the AACR has chosen to recognize Josh for his outstanding work,” says David Valle, M.D., the Henry J. Knott Professor and Director of the Institute for Genetic Medicine. “The microRNA field has really taken off, and Josh has been there to set the bar.”

This year’s AACR meeting, themed “Conquering Cancer Through Discovery Research,” highlighted novel approaches and technologies being used in the laboratory, innovative preclinical science and clinical trials. As the premier scientific meeting in cancer research, it attracts over 17,000 attendees annually and covers the breadth of cancer science from basic through clinical and epidemiological research.

“AACR member scientists are making great strides in basic, translational and clinical research, as well as population science and prevention,” says Margaret Foti, Ph.D., M.D., chief executive officer of the AACR. “Their work is having an enormous impact on the pace of discovery. We are extremely proud to honor their outstanding work because these achievements are saving lives around the world.”

On the Web:
Joshua Mendell: www.hopkinsmedicine.org/geneticmedicine/people/faculty/mendell.html
McKusick Nathans Institute of Genetic Medicine: www.hopkinsmedicine.org/geneticmedicine
American Association for Cancer Research: www.aacr.org/default.aspx
A Q&A with Joshua Mendell: www.hopkinsmedicine.org/geneticmedicine/news/ScientistInterviews/Joshua_Mendell.html
Related Video: http://www.youtube.com/watch?v=6f-5P076L8c
Joshua Mendell, M.D., Ph.D., explains microRNAs

Maryalice Yakutchik | Newswise Science News
Further information:
http://www.jhmi.edu

More articles from Awards Funding:

nachricht Six German-Russian Research Groups Receive Three Years of Funding
12.09.2017 | Hermann von Helmholtz-Gemeinschaft Deutscher Forschungszentren

nachricht IVAM Marketing Prize recognizes convincing technology marketing for the tenth time
22.08.2017 | IVAM Fachverband für Mikrotechnik

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

Im Focus: Fast, convenient & standardized: New lab innovation for automated tissue engineering & drug

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...

Im Focus: Silencing bacteria

HZI researchers pave the way for new agents that render hospital pathogens mute

Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...

Im Focus: Artificial Enzymes for Hydrogen Conversion

Scientists from the MPI for Chemical Energy Conversion report in the first issue of the new journal JOULE.

Cell Press has just released the first issue of Joule, a new journal dedicated to sustainable energy research. In this issue James Birrell, Olaf Rüdiger,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

IVAM’s LaserForum visits the Swiss canton of St. Gallen with the topic ultrashort pulse lasers

06.09.2017 | Event News

 
Latest News

The Wadden Sea and the Elbe Studied with Zeppelin, Drones and Research Ships

19.09.2017 | Earth Sciences

Digging sensors out of an efficiency hole

19.09.2017 | Materials Sciences

Solar wind impacts on giant 'space hurricanes' may affect satellite safety

19.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>