Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cancer Research Award to Johns Hopkins Basic Scientist

27.04.2010
Joshua T. Mendell, M.D., Ph.D., an associate professor in the McKusick-Nathans Institute of Genetic Medicine at the Johns Hopkins University School of Medicine, and a Howard Hughes Medical Institute Early Career Scientist, is the recipient of the 30th annual American Association for Cancer Research Award for Outstanding Achievement in Cancer Research. The award is for his work to advance the understanding of microRNAs (miRNAs), genetic signaling elements involved in gene “silencing,” which are important for normal physiology and diseases such as cancer.

The award, which comes with a $5,000 cash prize, was presented during the 101st annual meeting of the American Association for Cancer Research, at which Mendell delivered a lecture, “MicroRNA Reprogramming in Cancer: Mechanisms and Therapeutic Opportunities.” His recent research demonstrates that the delivery of microRNAs to cancer cells represents a promising strategy for cancer therapy.

“To be included among the incredible past recipients of this award — many of whom I view as scientific role models — is truly humbling and very exciting,” Mendell says. “This recognition suggests that our work has addressed important scientific questions that have had a broad impact on the cancer research community, and provides inspiration to continue to investigate fundamental questions in cancer biology.”

Mendell’s research focuses on short pieces of RNA that do not encode protein but control genes. These small molecules can act as either cancer-driving oncogenes or as tumor-suppressor genes, which prevent cells from becoming cancerous. Mendell’s laboratory is studying microRNAs in human cells and in animals such as zebrafish and mice to understand how aberrant miRNA activity contributes to cancer and to develop miRNA-based therapeutic strategies.

Mendell earned both his medical degree (2003) and a Ph.D. (2001) at Johns Hopkins before starting his lab there. He has received a number of awards and recognitions, including being named the Outstanding Young Scientist in the State of Maryland (Allan C. Davis Medal), 2007; a “Top Young Investigator of 2007” by Genome Technology Magazine, 2007; a Leukemia and Lymphoma Society Scholar, 2008; and a Howard Hughes Medical Institute Early Career Scientist, 2009.

“We are proud that the AACR has chosen to recognize Josh for his outstanding work,” says David Valle, M.D., the Henry J. Knott Professor and Director of the Institute for Genetic Medicine. “The microRNA field has really taken off, and Josh has been there to set the bar.”

This year’s AACR meeting, themed “Conquering Cancer Through Discovery Research,” highlighted novel approaches and technologies being used in the laboratory, innovative preclinical science and clinical trials. As the premier scientific meeting in cancer research, it attracts over 17,000 attendees annually and covers the breadth of cancer science from basic through clinical and epidemiological research.

“AACR member scientists are making great strides in basic, translational and clinical research, as well as population science and prevention,” says Margaret Foti, Ph.D., M.D., chief executive officer of the AACR. “Their work is having an enormous impact on the pace of discovery. We are extremely proud to honor their outstanding work because these achievements are saving lives around the world.”

On the Web:
Joshua Mendell: www.hopkinsmedicine.org/geneticmedicine/people/faculty/mendell.html
McKusick Nathans Institute of Genetic Medicine: www.hopkinsmedicine.org/geneticmedicine
American Association for Cancer Research: www.aacr.org/default.aspx
A Q&A with Joshua Mendell: www.hopkinsmedicine.org/geneticmedicine/news/ScientistInterviews/Joshua_Mendell.html
Related Video: http://www.youtube.com/watch?v=6f-5P076L8c
Joshua Mendell, M.D., Ph.D., explains microRNAs

Maryalice Yakutchik | Newswise Science News
Further information:
http://www.jhmi.edu

More articles from Awards Funding:

nachricht Yuan Chang and Patrick Moore win prize for the discovery of two cancer viruses
14.03.2017 | Goethe-Universität Frankfurt am Main

nachricht BMBF funding for diabetes research on pancreas chip
08.02.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

When Air is in Short Supply - Shedding light on plant stress reactions when oxygen runs short

23.03.2017 | Life Sciences

Researchers use light to remotely control curvature of plastics

23.03.2017 | Power and Electrical Engineering

Sea ice extent sinks to record lows at both poles

23.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>