Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cow’s resistance to worms is genetically determined

10.10.2003


Research carried out in the Netherlands has revealed that the genetic background of cattle apparently determines how quickly and effectively they acquire immunity to infections from gastrointestinal worms. Such infections cause considerable economic losses in the beef farming industry. During her doctoral research, Kirezi Kanobana investigated how cattle rid themselves of worms and prevent new infections.



Kanobana used an infection model in which, based on their genetic background, animals exhibited varying degrees of resistance to gastrointestinal worms. Broadly speaking there are three groups of animals. Two percent of the animals are naturally immune to a first infection. Another group reacts to the first infection with an effective immune response. In the event of a second infection these animals are protected. A third group is highly sensitive for infection and scarcely acquires any immunity even after repeated infections.

The researcher distinguished the three groups of animals by using two types of measurement. Three-month-old calves were infected with 100,000 larvae of a small-intestinal worm. After the infection an initial distinction was made on the basis of parasitological variables such as worm counts and the detection of eggs in the animals’ excreta. Secondly, immunological parameters were used to confirm the three groups of animals.


In an animal that has no resistance to a worm infection, the worms occur in the first part of the small intestine. In animals that develop resistance, worms are translocated towards the end of the small intestine.

Interestingly the male worms disappear out of the intestine first, followed by the female worms. This conclusion is based on a study six different parts of the small intestine, which in calves has a length of between 25 to 40 metres. In addition to this, Kanobana also discovered a number of mechanisms that are responsible for ensuring the disappearance of the worms from the small intestine.

Cattle pick up larvae from the grass, which develop into adult worms in the cattle’s gastrointestinal system. The worms reproduce sexually and lay eggs. The eggs pass out of the cattle with the excreta. In the dung, the eggs can once more develop into larvae. In this manner cattle can continually be reinfected by eating the grass.

Preventative anti-worm drugs are effective but are a potential risk to public health, as they are sometimes found in dairy and meat products. An understanding of how cattle acquire immunity might contribute to the development of a vaccine, which would be a good alternative for preventing gastrointestinal worm infections.

Sonja Jacobs | alfa
Further information:
http://www.nwo.nl

More articles from Agricultural and Forestry Science:

nachricht Light green plants save nitrogen without sacrificing photosynthetic efficiency
21.11.2017 | Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign

nachricht Filling intercropping info gap
16.11.2017 | American Society of Agronomy

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New proton record: Researchers measure magnetic moment with greatest possible precision

High-precision measurement of the g-factor eleven times more precise than before / Results indicate a strong similarity between protons and antiprotons

The magnetic moment of an individual proton is inconceivably small, but can still be quantified. The basis for undertaking this measurement was laid over ten...

Im Focus: Frictional Heat Powers Hydrothermal Activity on Enceladus

Computer simulation shows how the icy moon heats water in a porous rock core

Heat from the friction of rocks caused by tidal forces could be the “engine” for the hydrothermal activity on Saturn's moon Enceladus. This presupposes that...

Im Focus: Nanoparticles help with malaria diagnosis – new rapid test in development

The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

IceCube experiment finds Earth can block high-energy particles from nuclear reactions

24.11.2017 | Physics and Astronomy

A 'half-hearted' solution to one-sided heart failure

24.11.2017 | Health and Medicine

Heidelberg Researchers Study Unique Underwater Stalactites

24.11.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>