Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

A Breath Reveals a Hidden Image in Anti-Counterfeit Drug Labels

06.08.2014

An outline of Marilyn Monroe's iconic face appeared on the clear, plastic film when a researcher fogs it with her breath.

Terry Shyu, a doctoral student in chemical engineering at the University of Michigan, was demonstrating a new high-tech label for fighting drug counterfeiting. While the researchers don't envision movie stars on medicine bottles, but they used Monroe’s image to prove their concept.

Counterfeit drugs, which at best contain wrong doses and at worst are toxic, are thought to kill more than 700,000 people per year. While less than 1 percent of the U.S. pharmaceuticals market is believed to be counterfeit, it is a huge problem in the developing world where as much as a third of the available medicine is fake.

To fight back against these and other forms of counterfeiting, researchers at U-M and in South Korea have developed a way to make labels that change when you breathe on them, revealing a hidden image.

"One challenge in fighting counterfeiting is the need to stay ahead of the counterfeiters," said Nicholas Kotov, the Joseph B. and Florence V. Cejka Professor of Chemical Engineering who led the Michigan effort.

The method requires access to sophisticated equipment that can create very tiny features, roughly 500 times smaller than the width of a human hair. But once the template is made, labels can be printed in large rolls at a cost of roughly one dollar per square inch. That's cheap enough for companies to use in protecting the reputation of their products—and potentially the safety of their consumers.

"We use a molding process," Shyu said, noting that this inexpensive manufacturing technique is also used to make plastic cups.

The labels work because an array of tiny pillars on the top of a surface effectively hides images written on the material beneath. Shyu compares the texture of the pillars to a submicroscopic toothbrush. The hidden images appear when the pillars trap moisture.

"You can verify that you have the real product with just a breath of air," Kotov said.

The simple phenomenon could make it easy for buyers to avoid being fooled by fake packaging.

Previously, it was impossible to make nanopillars through cheap molding processes because the pillars were made from materials that preferred adhering to the mold rather than whatever surface they were supposed to cover. To overcome this challenge, the team developed a special blend of polyurethane and an adhesive.

The liquid polymer filled the mold, but as it cured, the material shrunk slightly. This allowed the pillars to release easily. They are also strong enough to withstand rubbing, ensuring that the label would survive some wear, such as would occur during shipping. The usual material for making nanopillars is too brittle to survive handling well.

The team demonstrated the nanopillars could stick to plastics, fabric, paper and metal, and they anticipate that the arrays will also transfer easily to glass and leather.

Following seed funding from the National Science Foundation's Innovation Corps program and DARPA's Small Business Technology Transfer program, the university is pursuing patent protection for the intellectual property and is seeking commercialization partners to help bring the technology to market.

This work is reported in Advanced Materials in a paper titled, "Shear-Resistant Scalable Nanopillar Arrays with LBL-Patterned Overt and Covert Images."

It was funded by the Defense Advanced Research Projects Agency; the National Science Foundation; the Korea Ministry of Science, Information and Communications Technology and Future Planning; the Ministry of Knowledge Economy; and the Korea Evaluation Institute of Industry Technology.

Nicole Casal Moore | newswise
Further information:
http://www.umich.edu

Further reports about: Advanced Materials Drug Technology materials nanopillars pharmaceuticals pillars special tiny

More articles from Materials Sciences:

nachricht OSU researchers prove magnetism can control heat, sound
29.05.2015 | Ohio Supercomputer Center

nachricht Engineering phase changes in nanoparticle arrays
26.05.2015 | DOE/Brookhaven National Laboratory

All articles from Materials Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Lasers are the key to mastering challenges in lightweight construction

Many joining and cutting processes are possible only with lasers. New technologies make it possible to manufacture metal components with hollow structures that are significantly lighter and yet just as stable as solid components. In addition, lasers can be used to combine various lightweight construction materials and steels with each other. The Fraunhofer Institute for Laser Technology ILT in Aachen is presenting a range of such solutions at the LASER World of Photonics trade fair from June 22 to 25, 2015 in Munich, Germany, (Hall A3, Stand 121).

Lightweight construction materials are popular: aluminum is used in the bodywork of cars, for example, and aircraft fuselages already consist in large part of...

Im Focus: Solid-state photonics goes extreme ultraviolet

Using ultrashort laser pulses, scientists in Max Planck Institute of Quantum Optics have demonstrated the emission of extreme ultraviolet radiation from thin dielectric films and have investigated the underlying mechanisms.

In 1961, only shortly after the invention of the first laser, scientists exposed silicon dioxide crystals (also known as quartz) to an intense ruby laser to...

Im Focus: Advance in regenerative medicine

The only professorship in Germany to date, one master's programme, one laboratory with worldwide unique equipment and the corresponding research results: The University of Würzburg is leading in the field of biofabrication.

Paul Dalton is presently the only professor of biofabrication in Germany. About a year ago, the Australian researcher relocated to the Würzburg department for...

Im Focus: Basel Physicists Develop Efficient Method of Signal Transmission from Nanocomponents

Physicists have developed an innovative method that could enable the efficient use of nanocomponents in electronic circuits. To achieve this, they have developed a layout in which a nanocomponent is connected to two electrical conductors, which uncouple the electrical signal in a highly efficient manner. The scientists at the Department of Physics and the Swiss Nanoscience Institute at the University of Basel have published their results in the scientific journal “Nature Communications” together with their colleagues from ETH Zurich.

Electronic components are becoming smaller and smaller. Components measuring just a few nanometers – the size of around ten atoms – are already being produced...

Im Focus: IoT-based Advanced Automobile Parking Navigation System

Development and implementation of an advanced automobile parking navigation platform for parking services

To fulfill the requirements of the industry, PolyU researchers developed the Advanced Automobile Parking Navigation Platform, which includes smart devices,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International symposium: trends in spatial analysis and modelling for a more sustainable land use

20.05.2015 | Event News

15th conference of the International Association of Colloid and Interface Scientists

18.05.2015 | Event News

EHFG 2015: Securing health in Europe. Balancing priorities, sharing responsibilities

12.05.2015 | Event News

 
Latest News

Quasi-sexual gene transfer drives genetic diversity of hot spring bacteria

29.05.2015 | Life Sciences

First Eastern Pacific tropical depression runs ahead of dawn

29.05.2015 | Earth Sciences

Donuts, math, and superdense teleportation of quantum information

29.05.2015 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>