Life Sciences and Chemistry

Self-repairing fenders and intelligent implants – shape-memory polymers as materials of the future

With a bang, the fender is dented and has to be replaced. Wouldn`t it be nice if the dent could simply – presto! – disappear? Such “intelligent” materials are already being developed, relate Andreas Lendlein and Steffen Kelch in an overview of the field in Angewandte Chemie.

Shape-memory polymers, that`s the magic words: after an undesired deformation, such as a dent in the fend

Scientists at the University of Virginia Health System have identified another step in the mysterious process of gene regulation — what turns genes on or off, making them cause or suppress disease and other physical developments in humans. As reported in this week’s issue of the scientific journal Nature, a chemical group called ubiquitin has been shown to lie upstream of a switch that seems to control whether a gene is on or off. “Ubiquitin was first discovered on histones long ago, but before thi

A newly developed polymer surface could improve the interface between electronic implants and living tissue, helping to advance a technology that may one day enable the blind to see and the paralyzed to walk. The findings were described today at the 34th Central Regional Meeting of the American Chemical Society, the world’s largest scientific society. The meeting is being held at Eastern Michigan University in Ypsilanti.

David C. Martin, Director of the Macromolecular Science and Engin

A study at Ohio State University is probing the nature of a unique sulfur-containing molecule — one that scientists consider a “missing link” in its chemical family.

The molecule, hydrogen thioperoxide, or HSOH for short, is related to the common bleaching and disinfectant agent hydrogen peroxide. Because HSOH contains sulfur, it could eventually help scientists understand how pollutants form in Earth’s atmosphere, and how similar molecules form in outer space.

Scientists

It’s a wonder cells make it through the day with the barrage of cues and messages they receive and transmit to direct the most basic and necessary functions of life. Such cell communication, or signal transduction, was at least thought to be an “automatic” cascade of biochemical events.

Now, however, a study reported in a recent issue of Nature by Johns Hopkins and Harvard scientists has found that even before a message makes it through the outer cell membrane to the inner nucleus, the

University of Michigan Kellogg Eye Center researchers have found that the aging of the human retina is accompanied by distinct changes in gene expression.

Using commercially available DNA slides, a team of researchers directed by Anand Swaroop, Ph.D., have established the first-ever gene profile of the aging human retina, an important step in understanding the mechanisms of aging and its impact on vision disorders.

In the August issue of Investigative Ophthalmology and Visual Scie