Technology Offerings
T-cell stimulatory peptides from the melanoma-associated chondroitin sulfate proteoglycan (MCSP)
The invention discloses a MCSP epitope recognized by CD4+ T lymphocytes. MCSP-specific T-cell clones from the peripheral blood of a healthy human donor could…
A receptor-dead mutein of bone morphogenetic protein 2 (BMP-2)
A new receptor-dead BMP-2 mutein L51P has been created that has no detectable BMP activity. Surprisingly, the BMP-2 L51P mutein exhibits an unaltered binding…
Bob-1 specific peptides and T-cells
The invention describes a method to identify T-cells (CTL, CD4+ T-helper), which are specifically directed to or have a highly specific cross-reactivity with…
Peptide-based method for monitoring gene expression in a host cell
The invention relates to a method for monitoring the expression level of a gene in a host by modulating the activity of a regulatory biomolecule. The…
TLR-MD2-fusion protein for the treatment of infectious diseases, chronic inflammatory diseases and sepsis
The recombinant TLR-MD-2 fusion protein or a fusion protein homopolymer / heteropolymer complex can be used for the prophylactic and/or therapeutic treatment…
New molecule class for transportation of drugs and antibodies into the cell nucleous
The novel conjugate molecules are provided for the manufacture of a medicament for gene therapy, apoptosis, or for the treatment of diseases such as cancer,…