This invention offers a new method for the direct and halogen-free formamide or acetamide formation of adamantane.
The adamantane modifications are chosen to enhance lipophilicity and stability of drugs, thereby improving their pharmacokinetics. Amido- and amino admantane derivatives can be used as drug delivery systems. They are able to overcome the blood-brain barrier and are competent to penetrate into the fatty tissue.
Due to these properties adamantane derivates are already used as therapeutics (e.g. for neurodegenerative diseases) and cosmetics. They are, for example, used as antiviral drugs or to treat Parkinson?s as well as Alzheimer?s diseases.

The building sector accounts for 40 percent of primary energy consumption in Europe. Home owners seeking for energy efficiency are faced with confusing and…

Thus the MeerKAT observatory in South Africa, has been chosen as a host for this receiver system. MeerKAT will be the most sensitive observatory of the…

Today sees the launch of a campaign to bring an end to the world water crisis by providing sustainable, pure drinking water to up to a billion people without a…

Driver assistance systems that recognise obstacles in road traffic, visual effects in films like Matrix, computer-animated characters and combined imaging…

HLRS’s new Cray XC40 system is based on the new Intel Xeon processors, formerly code-named “Haswell”, and the Cray Aries system interconnect. In its current…

This research is being carried out under the auspices of MAGDRIVE, a European research project coordinated by Professor José Luis Pérez Díaz, from the UC3M…

It consists of the development of a magnetic gear reducer, that is, a mechanism that transforms speed from an input axle to another in an output axle (as in a…

The transit of the exoplanet 55 Cancri e is the shallowest detected from the ground yet, and the success bodes well for characterizing the many small planets…

As a way of demonstrating the complicated shapes that ring-shaped polymers can adopt, the researchers have created a brand new type of ring-shaped pasta,…

MRIs are used predominantly in lung diagnostics. The innovation can be used as contrast agent. 3He is harmless when used as contrast agent and is already used in research for this purpose. Though modern MRIs can generate images from all body areas without any contrast agent, the use of 3He, in particular in examinations of the lungs, significantly increases the contrast and therefore the resolution, enabling cancer tumors or infections to be detected more efficiently.
Furthermore, the 3He magnetometer can be used in all forms of therapy that work using magnetic fields, such as thermotherapy with magnetic nanoparticles (nano-cancer therapy) that selectively impair tumor cells through heat. The magnetic fields used have to be adjusted individually before each therapy session.

In the analysis of biological samples, specimens are often investigated with methods in sequential order. In order to make this possible, the adequate preservation of samples is an essential prerequisite. A commonly used procedure is in this case the cooling of samples to -20° C to -80° C by freezing.
Disadvantageous is however so far that, due to insufficient thermal insulation sample temperatures gradually approximate the ambient temperature within the respective device. The sample to be investigated consequently thaws, which negatively influences the quality of downstream investigation procedures or even causes a destruction of the structural integrity of the specimen.
The invention solves this problem by the use of a hollow cylinder which consists of thermally insulating, X-ray translucent material as insulating body.

For the medical treatment of lung diseases pharmaceuticals are often applied by inhalation. The release of the active agent occurs within a very short time-period. If the release of the active agent is to be delayed in order to achieve a most uniform release during a longer period of time, aqueous dispersions of encapsulated active substances are used.
The basic idea of the innovation is the application of polymer solutions containing active substances and forming particles only after nebulisation at the intended site of deposition.

The ozone-based innovation allows to arrest progression of the tumor and to induce tumor regression up to a complete remission. The innovation comprises the utilization of a novel device for the application of an ozone- or ozonized oxygen-containing fluid in a human or animal torso or, more precisely, for intraperitoneal application, whereby application does not need to take place in immediate contact with the tumor in order to be effective.

Treatment with high energy radiation is a generally recognized method in cancer therapy. Instead of high energy radiation, particle therapy uses accelerated charged particles, such as protons or heavy ions (e.g. carbon). The difference between particle therapies in comparison to conventional radiotherapy is the deviant penetration behavior of the particles.The novel system provides the unique possibility of combined diagnosis and therapy by means of ion beams.

Just a little time after Rosetta lander „Philae“ touched down on a comet it was clear that the mission was not continuing as expected, because the lander…