New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders. James Shorter, Ph.D., assistant professor of…
The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of…
Colder-than-normal July sea surface temperatures in the tropical South Atlantic are linked to both increased monsoon rainfall and malaria epidemics in the arid…
Two million Americans are allergic to insect stings, an allergy which sends more than 500,000 people to the emergency room annually. Yet, according to a study…
Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more…
The study, which published online today in the journal Nature Neuroscience, could also open up treatment possibilities for both familial Parkinson's and the…
Many T cells of the immune system have the general ability to identify and destroy tumor cells. For this reason, medical scientists are trying to use the…
Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in…
A diagnostic “cocktail” containing a single drop of blood, a dribble of water, and a dose of DNA powder with gold particles could mean rapid diagnosis and…
The secrets of how this jawless vertebrate separated from the jawed vertebrates early in the evolutionary process will give insight to the ancestry of…
When Jim Thomas and his global team of researchers returned to the Madang Lagoon in Papua New Guinea, they discovered a treasure trove of new species unknown…
For the first time, scientists have shown that transplanted eyes located far outside the head in a vertebrate animal model can confer vision without a direct…
“Before this there were no known chemical probes for the more than 200 domains in the human genome that recognize methyl lysine. In that regard, it is a first…
Defective viruses have genetic mutations or deletions that eliminate their essential viral functions. They have been observed for many human pathogens and are…
The researchers report their findings in the current issue of The Journal of Neuroscience.“The development of this model could help scientists identify new…
Utilizing molecular analyses of gene expression in macrophages, which are cells largely responsible for inflammation, researchers have shown that inhibiting a…
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