Thousands of miles away in a lab tucked in Colorado's Rocky Mountains, scientists take data measurements and use the latest computer models to predict weather….
Obstructive sleep apnea is associated with an increased risk of stroke in middle-aged and older adults, especially men, according to new results from a…
Scientists at the Georg-August-University Göttingen produced different monoclonal antibodies directed against phosphorylation sites of CCR5. These antibodies have been demonstrated to exclusively recognise CD195 phosphorylated at Ser 337 or Ser 349. Human CD195 is a member of the G protein coupled superfamily of receptors, which acts as a receptor for a member of chemokines including RANTES and also serves as a co-receptor for the entry of HIV into cells. It plays a key role in regulating the activation and migration of leukocytes. CD195 is expressed by a subset of T-lymphocytes and by monocytes. Using these antibodies e.g. in combination with our indicator cell line ligand induced phosphorylation or dephosphorylation of CCR5 can be directly measured without using more indirect indicators like Ca++ concentrations.
This principle can be extended to measure activation states of G protein coupled receptors or activity of GPCR kinases generally, e.g. when screening for new agonists, antagonists or GRK inhibitors.
DASGIP AG, a leading provider of parallel benchtop bioreactor control systems, is now giving users of its technology online access to their bioprocesses via…
Scientists at the Georg-August-University produced a monoclonal antibody which recognises murine CD197, a 43kD member of the G coupled receptor family, which…
Scientists at the Georg-August-University Göttingen produced different monoclonal antibodies directed against phosphorylation sites of CCR5. These antibodies…
Scientists at the University of Göttingen developed new very light wood composites, boards and panels on renewable sources, replacing wood in a high percentage…
Scientists at the University of Göttingen identified a new use of Mediators and developed a binder-free production procedure of wood composites and timber…
Alzheimer's Disease (AD) is the main neurodegenerative disease worldwide affecting more than 15 Mill. people. An easy AD blood diagnostic method does not…
Chemist at the University of Göttingen developed a new family of polymerization catalyst.The new catalyst drastically reduces the amount of expensive…
The Mediterranean fruit fly (Medfly, Ceratitis capitata) is one of the most harmful food pests. Scientists at the University of Göttingen developed a new pest…
Pathogens like fungi fungi can cause dramatic damages in agriculture, resulting in critical losses of yield, quality and profit for most of the crops…
Scientists at the Univiversity of Göttingen, Germany, developed a New Procedure for the Reduction of the Formaldehyd Release in Wood Composites, based on the…
In the semiconductor industry the surfaces of silicon substrates are roughened in order to maximise the bonding of the additional layers required and the…
Softwood with increased Hardness and Durability
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The invention relates to a method of producing chlorophacinone which can be used as a stomach poison for controlling rodents. Further Information: PDF ESA…
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