A method has been developed that facilitates the individual prediction of forces affecting the dental bridges for each patient. In order to do so, the forces…
PLA2 enzymes cleave phospholipids at the sn-2-position.
They exist as secreted and cytosolic forms. The cytosolic
…
On the one hand, better water solubility of drugs leads to an improved bioavailability. Secondly, drug concentration for application can be decreased.
At…
The present invention consists of novel fluorescent dyes that primarily feature a large Stokes shift and long fluorescence lifetime. This is a nearly unique…
This invention is suitable for measuring the oxygen concentration in gas and liquids using optical fibre technology. Oxygen concentration measurement in…
The process permits an increased proportion of methane in biogas by introducing hydrogen into the biogas plant. The hydrogen is not pumped into the biogas…
The invention consists in a process and a device for the continuous liquefaction of biomass. An upward flow in the ambient liquid of the fermentor brings the…
The invention relates to an electrically conductive adhesive consisting of a conductive phase of carbon nanotubes distributed in a matrix. The carbon nanotubes…
The present invention is directed to a process for the diastereoselective synthesis of phosphorus compounds, particularly pronucleotides (nucleotide prodrugs)….
Sigma receptors have been in the focus of drug discovery
for several years, being classified into two subtypes,
…
The NMDA receptor, an ion channel consisting of four
protein subunits, is involved in the pathophysiology of
…
Frankfurt scientists have developed a novel orthogonal spin label for structural and functional analysis of proteins with electron paramagnetic resonance…
The invention relates to a new process for the continuous production of glycerol-tertiary-butyl-ether (GTBE) by
etherification of glycerol and isobutene.
…
Vascular disrupting agents (VDA) can overcome the multidrug resistance of tumors by targeting specifically tumor vasculature. The present invention relates to specific analogs of combretastatin in the treatment or prevention of cancer, including multidrug-resistant and combretastatin-refractory cancers.
Developmental Status: Pharmacodynamical and toxicological studies currently in the works , Animal data available, Further mouse studies on tumor xenografts from other entities planned, Compound samples available for testing
Search for novel natural products from the extracts of various parts of plants is still an important pillar of modern drug research. Plants of the families…
Plants are an important source of pharmacologically active substances. The tropical
lianas of the families Dioncophyllaceae and Ancistrocladaceae are rich in…
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