Young stars ejecting plasma could give us clues into the Sun’s past Kyoto, Japan — Down here on Earth we don’t usually notice, but the Sun is frequently ejecting huge masses of plasma into space. These are called coronal mass ejections (CMEs). They often occur together with sudden brightenings called flares, and sometimes extend far enough to disturb Earth’s magnetosphere, generating space weather phenomena including auroras or geomagnetic storms, and even damaging power grids on occasion. Scientists believe that when…
An international team of astronomers, including Dr Simon Vaughan from the University of Leicester's Department of Physics and Astronomy, has discovered a…
Many mysteries of nature are locked up in the world of the very small and the very fast. Chemical reactions and material phase transitions, for example, happen…
The experiment starts from the principle of a classic billiard table. An international team of physicists created a kind of miniature pool table where the…
By implementing an axial hydro cyclone desilting can be done within the pressure pipe of hydropower plants.
The device produces a heavy swirling flow, the particles are carried radially outwards due to the centrifugal force and extracted after a short pathway.
The development of receptor tyrosine-kinase inhibitors (TKIs) in recent decades was a major step forward in cancer treatment. However, despite their clinical efficacy, therapy with TKIs is limited by strong side effects (such as skin rash) and development of resistance. New approaches are required
to overcome these drawbacks. Complexing the TK Inhibitor with Cobalt (Co3+) inactivates the inhibitor until it is released under the hypoxic conditions in the target tumour tissue. This approach promises effective treatment with considerably limited side effects. These complexes can be used as an alternative to existing
Epidermal Growth Factor Receptor (EGFR) Inhibitors, and were effective in tumour cells that have become resistant to conventional Treatments due to EGFR mutations like T790M.
The bone drilling apparatus effectively prevents overheating of the bone tissue by individually adjusting the coolant supply to the heat developed during a procedure. It implements a real-time measurement device, drill and regulating device for the coolant
pumping system.
This new 2D-actuator enables ultrasonic assisted drilling, milling or grinding of brittle-hard materials like ceramic, glass, silicium carbides or hardened
steel. It can be used in combination with existing machining centres. Operating at low frequency it allows the compensation of thermal and geometric faults at the workpiece as well.
Security in data transfer is an important issue, and not only since the NSA scandal. Sometimes, however, the need for speed conflicts to a certain degree with…
A study of spiral galaxies seen edge-on has revealed that “halos” of cosmic rays and magnetic fields above and below the galaxies' disks are much more common…
The human integrin avß6, which is usually undetectable in normal adults’ cells, but highly upregulated in different types of cancer, is an emerging target for therapy as well as imaging across several common tumor types. However, only few ligands are known so far that are highly active for avß6 integrin and at the same time possess no binding affinity toward other RGD-recognizing integrins. Furthermore, their metabolic instability, their high molecular weight and the complexity of their structures limit their medical application.
This problem could now be solved by the present invention. The peptides according to the invention show a remarkable affinity for avß6 and high selectivity against other integrins.
Navigating the Web gets easier by the day as corporate monitoring of our emails and browsing habits fine-tune the algorithms that serve us personalized ads and…
“Six plus seven makes three – plus one carried over”, calculated Professor Hermann Kohlstedt, Head of the Nanoelectronic group at Kiel University. This…
The research reactor TRIGA at Johannes Gutenberg University Mainz (JGU) has reached a new milestone: after 50 years of consecutive operation, TRIGA Mainz…
A team of scientists from the University of Chicago and the Pennsylvania State University have accidentally discovered a new way of using light to draw and…
This robot uses neural schemes similar to humans to navigate an office environment. © 2015 A*STAR Institute for Infocomm Research
One important biosynthetic precursor of fatty alcohols is hydroxyalkanoyloxy alkanoic acid (HAA). HAA can be produced by microbes using sugars as substrate. Currently, no commercial production of HAA is established in the art and only few literature exist
that relates to HAA production. Due to their amphiphilic nature, HAA can be used as biosurfactant on one hand and as a precursor for the synthesis of alkanes, which can be used as fuel especially aviation fuel on the other hand.
The present invention provides a novel procedure for a selective and quantitative (> 1g/L) production of HAAs from biotechnological process engineering.
Industrial relevant strains like P. putida and E. coli have been tested and specific chain lengths of HAAs (short or long) can be obtained via direct product secretion into the media. Within one day, already 40% of theoretical product (in view of glucose as C-source) can be achieved.
On behalf of the University of Aachen, PROvendis offers access to rights for commercial use as well as the opportunity for further co-development.
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