Young stars ejecting plasma could give us clues into the Sun’s past Kyoto, Japan — Down here on Earth we don’t usually notice, but the Sun is frequently ejecting huge masses of plasma into space. These are called coronal mass ejections (CMEs). They often occur together with sudden brightenings called flares, and sometimes extend far enough to disturb Earth’s magnetosphere, generating space weather phenomena including auroras or geomagnetic storms, and even damaging power grids on occasion. Scientists believe that when…
“In this work, we have made two major advances–the ability to precisely control the brightness of light-emitting particles called quantum dots, and the…
For their experiments NIM-graduate student Stephan Kapfinger and his supervisor Hubert Krenner at the chair of Experimental Physics I (Prof. Achim Wixforth) at…
Electrons hit by strong laser pulses change their location on ultrashort timescales, i.e. within a couple of attoseconds (1 as = 10 to the minus 18 sec). In…
In quantum physics, electrons behave both as particles and as waves. The wave nature can be described by the spatial wave function, the orbital. “Orbitals…
In freeze substitution the water content in biological samples is replaced with a solvent (usually acetone or methanol) and is a notoriously slow technique. This invention significantly reduces the duration by agitating samples during the process.
Glutathione S-transferase P1 (GSTP1), applied as a recombinant protein, shows powerful longterm cardioprotective effects in a rat model for
myocardial infarction after a single application within 2 hours after infarction.
Researchers in an international collaboration at the Paul Scherrer Institute (PSI) have successfully developed a new experimental method to determine a…
Biotechnological expression of highly active proteins or small chemical compounds of pharmaceutical relevance is often difficult. Many proteins or molecules of interest (POIs/MOIs) have cytotoxic side effects and interfere with the host’s metabolism. The invention provides a versatile tool – based on a low-temperature inducible protein accumulation system (lt-degron) – and methods to generate so-called ‘phenotypes on demand’ for the production of POIs/MOIs in a spatial and time-dependent manner ensuring proper posttranslational modifications. For the first time, it has been adopted to multicellular organisms like insects and intact plants in vivo.
Fungi (yeast) of the genus Malassezia are found on the skin of most humans and animals. In humans this disease is most commonly caused by Malassezia furfur. Infections with this pathogen can result in life-threatening fungemia and other nosocomial infections. Rare cases can be attributed to M. pachydermatis. Novel natural substances are provided, which show highly promising activity against M. pachydermatis. MIC values are comparable to those for terbinafine, which is a synthetic antifungal.
In the digital age, data is becoming available in ever greater volumes, and the complexity of this data is increasing as well. At the same time, the number of…
Walking an obstacle course on Earth is relatively easy. Walking an obstacle course on Earth after being in space for six months is not quite as simple. The…
New software version 4.7 of the Sinumerik Operate user interface optimized for multitasking machine tools
Cross-technology, standardized look-and-feel for…
Cachexia related to cancer, occurs in 30-70% of cancer patients and still represents an as-yet non-curable and fatal paraneoplastic syndrome in a variety of tumor entities. The present invention discloses a new method for preventing cancer cachexia based on preventing inhibition of the protein AMPK.
6% of all prostate cancer patients die due to their illness. However, 80% of all prostate cancer patients do not need therapy, since their cancers grow slowly. Since the mainly used marker (prostate-specific antigen, PSA) is also elevated in case of inflammatory processes or with benign prostatic hyperplasia, DKFZ inventors analysed serum samples and identified miRNA-375 and miRNA-141 as new biomarkers for high-risk tumors.
DKFZ researchers identified nuclear receptor tailles (Tlx) as a valuable drug target for brain tumors especially gliobastomas. In vivo experiments showed almost doubling in survival time of mice harbouring brain tumors by inhibiting the expression of Tlx in tumor cells. In addition a highly significant correlation between expression of Tlx in brain tumor cells and survival of the patient was demonstrated.
Solar flares are powerful bursts of radiation. Harmful radiation from a flare cannot pass through Earth's atmosphere to physically affect humans on the ground,…
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