New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines Human astroviruses are a leading viral cause of the stomach bug—think vomiting, diarrhea, and fever. It often impacts young children and older adults, leading to vicious cycles of sickness and malnutrition, particularly for those in low and middle income countries. It’s very commonly found in wastewater studies, meaning it’s frequently circulating in communities. As of now, there are no vaccines for…
VILLARS-SUR-GLÂNE, SWITZERLAND, 2 September 2025 — A newly released Genomic Press Interview in Psychedelics spotlights groundbreaking findings from Professor Gregor Hasler that are redefining global mental health treatment. As Chair of Psychiatry at the University of Fribourg and Director of the Molecular Psychiatry Lab, Professor Hasler is pioneering a scientific movement that could transform outcomes for millions of patients suffering from treatment-resistant psychiatric conditions. The feature, part of the Innovators & Ideas series, presents decades of research demonstrating how psychedelics…
Nanoparticles power technologies from quantum-dot displays to catalysts and drug delivery. Their unique properties depend on size and shape, yet scientists have long struggled to explain why nanoparticles self-organize into uniform size ranges. For more than a century, the classical nucleation theory (CNT) has been the standard framework, but it cannot account for these dynamics. Now, researchers at Chung-Ang University (CAU), Seoul, together with collaborators from Seoul National University and the Institute for Basic Science (IBS), have developed a new…
When a tree dies, its remains become the foundation for new life. Leaves, wood, and roots gradually break down—not through weathering, but through the work of countless fungi, insects, and other tiny organisms. As they decompose plant material, these organisms release stored carbon back into the atmosphere, fueling photosynthesis and sustaining the global carbon cycle. But which organisms perform this critical work, and what molecular tools do they use? A research team at Goethe University Frankfurt has now developed a…
Too much fat can be harmful, and the way fat cells (adipocytes) form is critical for maintaining healthy fat tissue. A team led by researchers from the University Hospital Bonn (UKB) and the University of Bonn has studied how dysfunction in primary cilia—the antenna-like structures on precursor cells—affects fat cell development in mice. The study, published in The EMBO Journal, reveals that overactivation of the Hedgehog signaling pathway leads precursor cells to develop into connective tissue-like cells instead of white…
Researchers at the University of California, San Diego, Sanford Stem Cell Institute have devised an innovative technique to stimulate and mature human brain organoids utilising graphene, a monolayer of carbon atoms. The study, published in Nature Communications, presents Graphene-Mediated Optical Stimulation (GraMOS), a safe, non-genetic, biocompatible, and non-invasive method for modulating brain activity over periods of days to weeks. This method expedites the formation of brain organoids, which is particularly crucial for modelling age-associated disorders such as Alzheimer’s disease, and…
A prehistoric Yersinia pestis genome obtained from sheep sheds illuminates a previously enigmatic infectious illness that afflicted Eurasia for more than 2000 years. Key Points Approximately 5,000 years ago, an enigmatic epidemic disseminated across Eurasia, vanishing 2,000 years thereafter. This enigmatic ‘LNBA plague’ lineage, known solely from ancient DNA, has confounded experts regarding its probable zoonotic origin and transmission. A recent study published in Cell identifies this ancient plague in an animal for the first time: a 4,000-year-old domesticated sheep…
Researchers at Tsinghua University have devised a technique to cultivate kidney cancers in vitro, utilising cells from actual patients, presenting a promising new instrument in the battle against renal cancer. Their study, published in the journal Biofabrication, delineates how 3D bioprinting technology might be employed to recreate the distinct properties of each patient’s cancer. The team integrated cancer cells with several cell types, including structures resembling blood vessels, to replicate the in vivo environment. The lab-cultivated tumours, referred to as…
Omega-3 fatty acids are recognised as a vital component of a nutritious diet. Since humans are incapable of synthesising them, they must be ingested in adequate quantities. Nonetheless, omega-6, -7, -9, and -10 fatty acids are also crucial in lipid metabolism. These numbers denote the location of the initial double bond in a fatty acid chain. Alterations in the omega position may indicate enzymatic dysfunctions or abnormal metabolic processes, including those associated with cancer. Researchers at the University of Graz…
For 25 years, scientists at Northwestern Medicine have been investigating a remarkable group of individuals known as SuperAgers — people aged 80 and older whose memory functions match those of adults at least 30 years younger. These findings challenge the long-standing belief that significant memory decline is an inevitable part of aging. The study, which was published as a perspective article in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, was published in conjunction with the journal’s special issue…
Researchers at the University of California, Davis have uncovered key insights into how freshwater apple snails can fully regenerate their eyes — a rare ability that could one day inform treatments for human eye injuries. In a new study published on August 6 in Nature Communications, Assistant Professor Alice Accorsi and her team reveal that apple snail and human eyes are strikingly similar in both structure and genetics, positioning these snails as a promising model for eye regeneration research. “Apple…
A University of Queensland-led study has discovered that Australian skinks have independently evolved molecular adaptations that protect them from the paralysing effects of snake venom. This remarkable evolutionary trait allows the reptiles to survive encounters with some of Australia’s most venomous predators. Unlocking the Molecular Secrets of Resistance Lead researcher Professor Bryan Fry from UQ’s School of the Environment explained that the skinks’ resistance lies in small but critical mutations in a receptor known as the nicotinic acetylcholine receptor—the very…
The percentage of babies in Sweden who receive antibiotics to treat suspected sepsis varies significantly by region, according to a recent study from the University of Gothenburg. In addition to emphasising areas that exhibit outstanding practices, the researchers hope to raise awareness of the problem of overprescribing. The main reason antibiotics are given to infants is to treat suspected sepsis, a dangerous illness that needs to be treated right away. Even while sepsis occurrences have been progressively declining over time,…
Recent research uncovers an unexpected connection between advantageous and detrimental gut bacteria that could facilitate tailored strategies for enhancing intestinal health. The human gastrointestinal tract harbours trillions of bacteria that are crucial for digesting, immunological control, and overall health. An imbalance in the composition or variety of these microbes, referred to as gut microbiota dysbiosis, has been associated with numerous digestive problems and diseases. Nevertheless, scientists have not yet comprehensively elucidated the mechanisms by which these bacteria interact to preserve…
The cerebral cortex processes sensory information through a sophisticated network of neuronal connections. In what manner are these signals modified to enhance perception? A team from the University of Geneva (UNIGE) has discovered a method via which specific thalamic inputs influence neurones and alter their activity. This study, published in Nature Communications, uncovers an unrecognised mode of communication between the thalamus and the somatosensory cortex. This may elucidate why identical sensory stimuli do not consistently provoke the same sensation and…
Millipedes might not be anyone’s favorite creatures — with their countless legs and secretive behavior, they often fall into the category of “creepy crawlies.” But new research suggests that these arthropods could be unexpected allies in the search for treatments for neurological disorders and pain. Chemist Emily Mevers and her research team have identified a new group of complex chemical structures in millipede secretions that can influence specific neuroreceptors in ant brains. These molecules belong to a class of naturally…
Advancements in precision cancer treatment are progressing as researchers have created an AI platform capable of customising protein components and enhancing the patient’s immune cells to combat cancer. The novel technique, published in the journal Science, illustrates for the first time the feasibility of computer-designed proteins to steer immune cells towards cancer cells using pMHC molecules. This significantly reduces the duration required to identify effective compounds for cancer treatment from years to mere weeks. “We are essentially creating a new…