By combining in-field experiment, laboratory simulations, and theoretical calculations, this work identifies a new pathway of photochemical conversion of atmospheric chlorinated organics into polychlorinated dibenzo-p-dioxins and dibenzofurans on mineral dust particulates, underscoring the need to reassess the toxicity of commercial chlorinated organics and their secondary transformation particulates in the atmosphere. Photo Credit: Angewandte Chemie

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Health & Life

Life & Chemistry
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Are We Missing the Real Risk of Industrial Air Pollutants?

Chlorinated organic substances can be converted into dioxins in the atmosphere Are the risks of hazardous chemicals being determined appropriately? In certain cases, apparently not–according to a study published in the journal Angewandte Chemie by a team of Chinese researchers. The study indicates that chlorinated volatile organic compounds on mineral dust particles in the atmosphere can be converted into highly toxic polychlorinated dibenzo-p-dioxins and dibenzofurans by sunlight. Hazardous chemicals are frequently assessed under national and international regulatory frameworks, which primarily…

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A cartoon of graphene membrane separating CO2 from N2. Credit: Ivan Savicev (EPFL)
Life & Chemistry

Scalable Graphene Membranes Boost Carbon Capture Efficiency

Capturing carbon dioxide (CO₂) from industrial emissions is crucial in the fight against climate change. But current methods, like chemical absorption, are expensive and energy-intensive. Scientists have long eyed graphene—an atom-thin, ultra-strong material—as a promising alternative for gas separation, but making large-area, efficient graphene membranes has been a challenge. Now, a team at EPFL, led by Professor Kumar Agrawal, has developed a scalable technique to create porous graphene membranes that selectively filter CO₂ from gas mixtures. Their approach slashes production…

Engineering Smart Delivery for Gene Editors
Health & Medicine

Smart Delivery Solutions for Gene Editors in Engineering

A research team from Helmholtz Munich and the Technical University of Munich has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater efficiency than before. Their technology, ENVLPE, uses engineered non-infectious virus-like particles to precisely correct defective genes – demonstrated successfully in living mouse models that are blind due to a mutation. This system also holds promise for advancing cancer therapy by enabling precise genetic manipulation of engineered…

Professor Mathew Upton, Professor of Medical Microbiology at the University of Plymouth and Chief Scientific Officer at Amprologix Credit: University of Plymouth
Health & Medicine

New Antibiotic Class Shows Promise Against MRSA Infections

The development of new antibiotics to treat superbugs and other bacterial infections is a global priority, with the rate of infections that cannot be treated with current antibiotics rising and presenting one of the biggest threats to human health. In line with that, new research has shown a daily dose of epidermicin NI01 – an antibiotic compound developed by University of Plymouth spinout company Amprologix – is as effective at removing Methicillin-resistant Staphylococcus aureus (MRSA) as the current standard of…

Chemicals used in different applications induce genetic and epigenetic aberrations implicated in various diseases, including cancer. Researchers from Japan have developed a cell-based reporter assay for quantification of chemical-induced epigenetic alterations that can enhance the safety evaluation of potential carcinogens. Credit: Associate Professor Akira Sassa from Chiba University, Japan
Life & Chemistry

Affordable Reporter Assay for Evaluating Epigenetic Changes

Researchers developed a cell-based reporter assay that can quantify epigenetic changes induced by chemicals and potential carcinogens Chemicals used as food preservatives, flavoring agents, dyes, pesticides, cosmetics, cleaners, and other industrial materials are being increasingly recognized as a health hazard. Their rampant use has led to an increase in the prevalence of various chemical toxicity-induced diseases, including hormonal disruption, cancer, neurological disorders, skin conditions, and occupational poisoning. Numerous chemicals are known to trigger “carcinogenesis” or cancer development by exerting genotoxic…

New solutions for the RNA medicine of the future
Health & Medicine

Shaping the Future of Medicine: How Young Scientists Are Reinventing RNA Therapies for the Heart and Beyond

At the RNApp graduate school, young researchers are working to make RNA-based drugs safer and more effective. Ribonucleic acid (RNA) is an important component of our cells. As messenger RNA (mRNA), it is the blueprint for translating genetic information into proteins. This process can also be used medically to produce specific proteins. One well-known application is mRNA vaccines against coronaviruses. There is also so-called non-coding RNA (ncRNA), which does not contain protein blueprints but instead takes over control mechanisms in…

In a recent review article, a research team outlined recent progress in transition metal-free techniques to achieve coupling. Their combined efforts in these methods could help minimize waste and greatly increase energy and efficiency, helping us realize coupling processes for the pharmaceutical and fine chemical industries that better align with sustainability principles. Credit: Dr. Toshifumi Dohi and Dr. Yasuyuki Kita from Ritsumeikan University, Japan
Life & Chemistry

Rethinking Coupling Methods for Sustainable Organic Synthesis

Researchers explore transition metal-free strategies to reduce environmental impact and enhance efficiency in pharmaceutical and fine chemical industries Coupling reactions are among the most transformative tools in organic chemistry, enabling the formation of crucial chemical bonds in pharmaceuticals, agrochemicals, and advanced materials. Since their introduction, they have been one of the backbones of modern organic synthesis. However, these methods have long relied on environmentally taxing transition metal catalysts, such as palladium, which are often scarce, costly, and generate unwanted byproducts….

Dr Aidan Cousins, Dr Nicole Dmochowska and Professor Benjamin Thierry are working on new technology to improve cancer treatment. Credit: University of South Australia
Health & Medicine

New Tool Promises Significant Advances in Cancer Treatment

New Australian technology is set to transform the way that gastrointestinal cancers are detected and treated with precise, minimally invasive surgery. Backed by the Federal Government’s Economic Accelerator (AEA) Ignite Grant, researchers from the University of South Australia (UniSA) are using quantum technology to develop a first-of-its-kind laparoscopic probe that will allow surgeons to accurately map the spread of tumours. The technology has the potential to improve cancer survival rates and patient quality of life worldwide. Led by Dr Nicole…

How cells repair their power plants
Health & Medicine

Uncovering Mitochondria’s Recycling Power: A Key to Fighting Age-Related Diseases

Medicine: Publication in Science Advances Damage to the mitochondria, the “power plants” of the cells, contributes to many diseases. Researchers from Heinrich Heine University Düsseldorf (HHU) and the University of Cologne led by HHU professor of medicine Dr David Pla-Martín, now describe in the scientific journal Science Advances how cells with defective mitochondria activate a special recycling system to eliminate damaged genetic material. Damage to the genetic material of mitochondria – the mitochondrial DNA or mtDNA for short – can…

Blue arrows point to normal pancreatic ductal mouse cells. Yellow arrows point to cells undergoing acinar-to-ductal metaplasia. Credit: Johns Hopkins Medicine
Health & Medicine

Pancreatic Cells Retain Epigenetic Marks Without DNA Changes

Study led by Johns Hopkins researchers may advance efforts to reveal how epigenetic events contribute to cancer development Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic “marks” in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a temporary “memory” of those cancer-linked marks. Epigenetic marks are chemical modifications that help regulate genetic expression without directly altering DNA sequence in the makeup of genes….

Portrait image of Valdemar Landgren
Health & Medicine

Raising Awareness: Prevalence of Fetal Alcohol Spectrum Disorder in Sweden’s Schoolchildren

Out of 206 fourth-grade students, 19 met criteria for fetal alcohol spectrum disorders. This was found in a pilot study conducted at the University of Gothenburg. The results indicate that birth defects caused by alcohol consumption during pregnancy may be as common in Sweden as in several other European countries. The study ran at six schools in western Sweden and constituted an add-on to the regular health check-up for all fourth-grade students. The participants underwent a physical examination, review of…

Syringes; photo by Dr. Edward Murphy Credit: Syringes; photo by Dr. Edward Murphy
Health & Medicine

Innovative Solutions to Syringe Access in Pharmacies

More than two-fifths of Oregon community pharmacies require a prescription to purchase syringes, even though they can be sold over the counter, creating an access barrier that could exacerbate the spread of bloodborne diseases like hepatitis C. Oregon State University researchers conducted a telephone survey of more than 400 pharmacies in Oregon and learned that 43% of them were unwilling to sell a 10-pack of syringes to someone without a prescription. The scientists say the study was the largest to…

Researchers at The University of Texas at Dallas have fused chemistry with technology to create a 3D-printed foam that is more durable and more recyclable than the polymer foam found in many everyday products. The research, which appears in the March 1 print edition ofRSC Applied Polymers, focused on creating a sturdy but lightweight foam that could be 3D-printed. Credit: University of Texas at Dallas
Life & Chemistry

3D-Printing Formula Could Transform Future Foam Innovations

From seat cushions to mattresses to insulation, foam is everywhere — even if we don’t always see it. Now, researchers at The University of Texas at Dallas have fused chemistry with technology to create a 3D-printed foam that is more durable and more recyclable than the polymer foam found in many everyday products. The research, which appears in the March 1 print edition of RSC Applied Polymers, a journal of the Royal Society of Chemistry, focused on creating a sturdy but lightweight foam…

Volatile fatty acid separation from biowaste. Cattle manure is anaerobically digested in a bioreactor, and the resulting broth is processed with redox-mediated electrodialysis. The volatile fatty acids pass through the selective filters. Credit: The Grainger College of Engineering at the University of Illinois Urbana-Champaign
Life & Chemistry

Innovative Process Extracts Valuable Chemicals from Animal Waste

A collaboration between chemical engineers and animal scientists has created a system for recovering valuable industrial chemicals from animal waste, representing a major step towards circularity and environmental sustainability. Researchers at the University of Illinois Urbana-Champaign have developed a nanofiltration system for separating volatile fatty acids (VFAs) – organic molecules that are critical in fine chemical production across many sectors – from cattle manure fermented in bioreactors. Thanks to the incorporation of selective ion-exchange membranes into an electrochemical separation system,…

A graphic representation of the starfish-inspired wearable device alongside biological starfish. Credit: Courtesy of Zheng Yan
Medical Engineering

Starfish-Inspired Wearable Tech Innovates Heart Monitoring

Designed by University of Missouri researchers, the device includes AI technology to detect potential heart problems with over 90% accuracy, making it a promising tool for at-home monitoring When we move, it’s harder for existing wearable devices to accurately track our heart activity. But University of Missouri researchers found that a starfish’s five-arm shape helps solve this problem. Inspired by how a starfish flips itself over — shrinking one of its arms and using the others in a coordinated motion…

Brookhaven National Laboratory Distinguished Chemist James Wishart at theLaser Electron Accelerator Facility(LEAF), one of two facilities his team used to track chromium chemistry in molten salts. Credit: Roger Stoutenburgh/Brookhaven National Laboratory
Life & Chemistry

Tracking Chromium Chemistry in Irradiated Molten Salts

Findings show that radiation-induced chemistry may mitigate metal alloy corrosion in nuclear reactors cooled by molten salts High temperatures and ionizing radiation create extremely corrosive environments inside a nuclear reactor. To design long-lasting reactors, scientists must understand how radiation-induced chemical reactions impact structural materials. Chemists at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory and Idaho National Laboratory recently performed experiments showing that radiation-induced reactions may help mitigate the corrosion of reactor metals in a new type of reactor…

Dr. James Lim, associate professor of pediatrics at UBC’s faculty of medicine, observes pediatric cancer cells grown in a chicken egg under a microscope. Credit: Paul Joseph/UBC
Medical Engineering

New Method Matches Young Cancer Patients to Effective Drugs

A pan-Canadian team has developed a new way to quickly find personalized treatments for young cancer patients, by growing their tumours in chicken eggs and analyzing their proteins. The team, led by researchers from the University of British Columbia and BC Children’s Hospital Research Institute, is the first in Canada to combine these two techniques to identify and test a drug for a young patient’s tumour in time for their treatment. Their success in finding a new drug for the…

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