Researchers from the Keck School of Medicine of USC found that obesity, gestational diabetes and hypertensive disorders of pregnancy were tied to elevated blood pressure in offspring, with effects that grow as children age. Children born to mothers with obesity, gestational diabetes mellitus or a hypertensive disorder of pregnancy have higher systolic and diastolic blood pressure than children born to mothers without these risk factors, according to a new USC study. Among children whose mothers had at least one risk…
A team of researchers from the Department of Diagnostic and Therapeutic Ultrasonography at the Tianjin Medical University Cancer Institute & Hospital, have published a review (DOI: 10.20892/j.issn.2095-3941.2024.0376) in Cancer Biology & Medicine. The paper underscores the potential of AI to decode complex biological data with unprecedented speed and accuracy. By integrating genomics, medical imaging, and pathology at scale, AI is paving the way for data-driven strategies that bring precision medicine from theory into real-world clinical practice. In the realm of…
In an effort to curb misuse of opioids and prevent overdose deaths, the College of Physicians and Surgeons of British Columbia released a legally enforceable practice standard, Safe Prescribing of Drugs with Potential for Misuse/Diversion, in 2016. This document limited prescribing of opioids for chronic noncancer pain (CNCP) with specific prescribing practices that clinicians were obligated to follow. In research that tested the effects of the 2016 practice standard on prescribing to patients with CNCP, researchers found that its introduction had…
Per- and polyfluoroalkyl substances (PFAS) are ubiquitous, accumulate in the environment and are difficult to break down. They are known as “forever chemicals”. PFAS can compromise the immune system and thus, human health. In their current study, researchers from the Helmholtz Centre for Environmental Research (UFZ) show that high PFAS exposure has a negative effect on the cellular immune response to the SARS-CoV-2 coronavirus. The scientists suspect that people exposed to high levels of PFAS may have a suboptimal immune…
New UBuffalo research indicates that while the residential segregation policy was outlawed decades ago, it still impacts women’s health today BUFFALO, N.Y. – In neighborhoods across America, women face a daunting threat from a federal practice that, although it was outlawed decades ago, continues to negatively impact their health today. That’s according to the findings of new University at Buffalo research that examines how historical redlining — the federal policy from the 1930s where neighborhoods were given mortgage security grades…
We report that METTL3, an oncogene regulates the expression of SMAD4, a tumor-suppressor via miR-146a-5p, thus unveiling a novel regulatory axis of METTL3/miR-146a-5p/SMAD4 in OSCC, which can potentially have therapeutic implications BUFFALO, NY – May 9, 2025 – A new research paper was published in Oncotarget, Volume 16, on May 8, 2025, titled “METTL3 promotes oral squamous cell carcinoma by regulating miR-146a-5p/SMAD4 axis.” In this study, researchers Jayasree Peroth Jayaprakash, Pragati Karemore, and Piyush Khandelia from the Birla Institute of Technology and Science, India,…
In pancreatic ductal adenocarcinoma (PDA), the abnormal colonization of fungal communities has become a research hotspot. Compared to normal tissue, the abundance of fungi in tumor tissues of PDA patients increased by up to 3000 times, with the enrichment of Malassezia being particularly significant. These fungi activate the host complement system (such as the MBL-C3 pathway), triggering local inflammatory responses and promoting tumor growth. This indicates that Malassezia is not only a “marker” in the tumor microenvironment but also a…
MAY 9, 2025, NEW YORK – A Ludwig Cancer Research study has identified a key mechanism by which advanced ovarian cancers suppress anti-tumor immune responses and resist immunotherapies. Led by Ludwig Princeton’s Lydia Lynch and reported in the current issue of Science Immunology, the study details how ascites fluid—produced in large quantities as ovarian cancer spreads from the ovaries into the abdomen and its organs—sabotages cytotoxic lymphocytes, a class of immune cells that kill cancer cells. “Although ascites fluid has…
Women who experience significant weight gain after the age of 20 and either have their first child after the age of 30 or don’t have children are almost three times more likely to develop breast cancer than those who give birth earlier and whose weight remains relatively stable, new research from the UK being presented at this year’s European Congress on Obesity (ECO 2025) has found. Previous research has shown that weight gain in adulthood increases the risk of developing…
Miniaturized Iontronic Micropipettes for Precise and Dynamic Ionic Modulation of Neuronal and Astrocytic Activity Researchers at Linköping University have developed a new type of pipette that can deliver ions to individual neurons without affecting the sensitive extracellular milieu. Controlling the concentration of different ions can provide important insights into how individual braincells are affected, and how cells work together. The pipette could also be used for treatments. Their study has been published in the journal Small. “In the long term,…
Researchers at Umeå University, Sweden, and Michigan State University, USA, have discovered a type of molecule that can kill chlamydia bacteria but spare bacteria that are important for health. The discovery opens the door for further research towards developing new antibiotics against chlamydia, the world’s most common bacterial sexually transmitted disease with 130 million cases a year. “No one should have to live with chlamydia. But the problem is that the treatments we have today do not distinguish between dangerous…
A landmark study exploring Canadians’ consumption of chips, frozen pizzas, breakfast cereals and other ultra-processed foods typically loaded with fat, sugar and additives has confirmed these foods are directly and significantly linked to poor health outcomes. Researchers at McMaster University investigated the relationship between ultra-processed food (UPF) consumption and risk factors including blood pressure, cholesterol levels (LDL and HDL), waist circumference and body mass index (BMI). Their study is the first in Canada to leverage population-based and robust biomarker data…
Surgical face masks help prevent the spread of airborne pathogens and therefore were ubiquitous during the COVID-19 pandemic. Now, a modified mask could also protect a wearer by detecting health conditions, including chronic kidney disease. Researchers reporting in ACS Sensors incorporated a specialized breath sensor within the fabric of a face mask to detect metabolites associated with the disease. In initial tests, the sensor correctly identified people with the condition most of the time. Kidneys remove waste products made by…
First-of-its-kind research links a specific food in maternal diet to lower odds of food allergies in child’s first year of life MISSION VIEJO, Calif. (May 7, 2025) — An observational study among 2,272 mother-child pairs in Finland found that infants had 44% lower odds of developing food allergies at 12 months if their mother consumed fresh avocado during pregnancy, after adjusting for other lifestyle, delivery, and maternal health factors. Decades of research have explored the relationship between maternal diet and…
MIT chemists found a way to identify a complex sugar molecule in the cell walls of Mycobacterium tuberculosis, the world’s deadliest pathogen. CAMBRIDGE, MA — Tuberculosis, the world’s deadliest infectious disease, is estimated to infect around 10 million people each year, and kills more than 1 million annually. Once established in the lungs, the bacteria’s thick cell wall helps it to fight off the host immune system. Much of that cell wall is made from complex sugar molecules known as glycans,…
Harvard’s Dr. Michael Wheeler illuminates how psychedelic compounds interact with brain-immune pathways to potentially treat both psychiatric and inflammatory disorders BOSTON, Massachusetts, USA, 6 May 2025 — In a compelling Genomic Press interview published today, rising scientific star Dr. Michael Wheeler unveils revolutionary findings about how psychedelics reshape communication between the brain and immune system, potentially transforming treatments for psychiatric disorders and inflammatory diseases alike. Bridging the Mind-Body Divide As an Assistant Professor at Harvard Medical School and investigator at…
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