The effect of the intravenously administered fibrinogen IIb/IIIa receptor antagonist Tirofiban as a thrombocyte aggregation inhibitor is known and well investigated. Now, for the first time, the dispersal of Tirofiban in the form of an aerosol has been achieved, which allows application of the produced aerosol via inhalation. This has the advantage that the active ingredients are reabsorbed very quickly after deposition and rapidly reach a therapeutically active drug level in the blood, which leads to life-saving thrombocyte aggregation inhibition. With this the possibility for acute and immediate treatment of diseases which are caused by or in conjunction with thrombus formation is finally available.
All previously known synthesis procedures for the production of adamantane derivatives require drastic reaction conditions like, for example, the use of…
The treatment of lung and respiratory diseases, such as asthma and Chronic Obstructive Pulmonary Disease (COPD), pneumonia and pulmonary hypertension, is…
Self-assembling monolayers (SAMs) allow for the targeted modification of surface areas. Previously known methods for the production of SAMs are carried out…
The invention at hand provides novel, very hydrophobic ionic liquids as well as methods for the production thereof.<p>
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There are already several methods for the introduction of modifications in proteins which make use of the particular nucleophilicity of the cysteine side…
Hollow fibres with inner diameters under 0,1 mm are versatile materials, which are already being used as separation and storage media, for the treatment of…
Meso- and nanotubes with different layers have been used for some time for the production of hollow fibres and non-wovens. These non-wovens and the hollow…
The new procedure enables the production of tailor-made moulds with functional inner coatings. In contrast to previous production procedures, multiple coating…
The purpose of the invention at hand is a novel procedure for the separation of polymer systems with respect to molecular weight, chemical structure, chain…
The device will be operated by a modular composed measuring station combined with a dynamic nuclear spin tomograph, a software to analyse the measurement of…
A microsensor with a new type of silicone gasket permits for the first time the direct and continuous determination of gases beyond single stomata of leaves….
Short meso- and nanofibers have a multitude of potential applications, for instance in optics, electronics, in filtration applications and galenics. However,…
Die Erfindung betrifft eine aktive Computational Map mit der prinzipiell sowohl akustische als auch optische Muster nach Programmierung der Map in einem…
The subject-matter of the invention at hand is the laterally resolved, three-dimensional mass spectrometric imaging. The sample to be analysed is located on a…
Microparticles are particles in which an active agent is immobilized by means of a shell or coating. As a rule, the coating or shell is made of a cross-linked…
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