Kathrin Ohla, the lead researcher on the team, said: “The ability to taste is crucial for food choice and the formation of food preferences. Impairments in…
Nerve cells are wire-like conductors that transmit and receive signals in the form of electrical impulses. This function can be impaired by accidents or…
Atoms can lose many of their electrons at very high temperatures, forming highly-charged ions (HCIs). Such HCIs constitute a large class of atomic systems…
The kidneys and urinary tract are the sites affected most frequently by congenital malformations. Approximately 1 out of every 200 children suffers from such a…
“When the great air streams in the sky above us get disturbed by climate change, this can have severe effects on the ground,” says lead-author Dim Coumou….
Many organic pollutants that originate from industrial and technical processes, are persistent and are not degraded in the environment. This poses a hazard for…
The inventive method allows the context-sensitive indexing of hemodynamic parameters. For the indexation of hemodynamic and biochemical parameters a more specific adjustment based also on non-biometric data can be used to more accurately assess and easily access the parameters and thus simplify and improve the care of critically ill patients.
To boost the traction power supply network, the local transport authority Trafikverket has tasked Siemens with setting up a Sitras SFC plus static frequency…
Siemens builds an open cloud platform for analyzing large datasets in industry. This will provide a platform for data-based services such as Siemens offers for…
Moguntinones, a class of small molecule compounds comprise 3-(indolyl)- or 3-(azaindolyl)-4-arylmaleimide derivatives with tumor and vascular targeting properties. The present invention relates to the use of Moguntinones for treatment of colorectal or gastric adenocarcinoma.
Tumor growth and metastasis are highly associated with the overexpression of protein kinases. Therefore protein kinases are an interesting class of target molecules for improved therapeutic attempts. These proteins are known to regulate the majority of cellular pathways including such relevant for control cell growth, movement and death – all processes relevant for cancer growth and progression.
A physiological process focused on in development of anti-cancer agents is apoptosis, a controlled form of cell death eliminating damaged, aberrant, infected, old or superfluous cells. In particular often mucosa tissue such as gastrointestinal mucosa is characterized by a rapid epithelial cell turnover in which homeostasis is maintained predominantly by apoptosis.
One essential prerequisite for growth and metastasis of cancers which form tumors is angiogenesis, a process involving the formation of new blood vessels from pre-existing capillary endothelial cells. Tumor cells may enhance angiogenesis by overexpression of proangiogenic factors, e.g. VEGF or interleukins. In general, this is especially pronounced with tumors having a high microvessel density as well as a particular aggressive behavior and high tendency to metastasize. Therefore, inhibitors of angiogenesis are researched as antitumor agents.
[Ref. UMZ252]
As a novel energy storage device, supercapacitors have attracted substantial attention in recent years due to their ultra-high charge and discharge rate,…
Scientists at Johns Hopkins have created a 3-D model of a complex protein machine, ORC, which helps prepare DNA to be duplicated. Like an image of a criminal…
Devastating floodwaters such as those experienced during Iowa's Flood of 2008 — which swamped many Iowa communities, along with ten square miles of Cedar…
All you need is basic musical knowledge, your instrument, and a mobile device. With several entertaining lessons, you will learn to improvise and improve your…
Scientists in Haifa and Saarbrücken have now succeeded in replicating the combination of calcium carbonate and biopolymeric compounds which nature took…
A group of researchers at the Korea Advanced Institute of Science and Technology (KAIST) developed a high-performance ultrathin polymeric insulator for…
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