Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Portable stimulator being tested on Parkinson patients

21.01.2015

Researchers at the Sahlgrenska Academy have shown that a weak electric “noise” can improve balance and motor skills in patients with Parkinson’s disease. In cooperation with NASA, the research team has now developed a portable prototype that will be used in long-term studies of Parkinson’s patients in their home environment. The work has been published online in Brain Stimulation.

Parkinson’s disease is a slowly degenerative neurological disease that is expressed as impaired motor control, tremors, stiffness and, in later stages, problems with balance.


Filip Bergquist, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg

University of Gothenburg

The symptoms are caused by a lack of the signal substance dopamine and is traditionally treated with medication. However, balance problems do usually not improve much with pharmacological treatment.

Change brain activity
In earlier experiments on rats, researchers at the Sahlgrenska Academy showed that noisy electric stimulation of the balance organs can be used to change the activity of the brain, thereby balancing the effects of dopamine shortage and improve the animals’ motor skills and balance.

The researchers have now tested the same method on ten Swedish Parkinson’s patients.

Improved balance
The patients were studied in both medicated and unmedicated states. On one day, the patients received an active noise stimulation and on another day inactive treatment, blinded to which day the current was active. The experiments show that the active noise stimulation improved both the patients’ balance and the combined symptoms.

“The effect on balance was particularly apparent when the patients were in the unmedicated state, which is very positive,” says Associate Professor Filip Bergquist at the Sahlgrenska Academy who led the study.

Pocket stimulator
In a follow-up study over a longer time, the researchers will now have the Parkinson’s patients wear a stimulator that is smaller than a wallet and can be carried in the pocket.

“If the long-term treatment improves the patients’ walking, balance and symptom variations, we could in the next five years develop the noise stimulation technique and introduce it as a new treatment,” says Filip Bergquist.

The current study is published in the scientific journal Brain Stimulation and was conducted in cooperation with researchers at NASA, who also helped with technical equipment.

The article Effects of Stochastic Vestibular Galvanic Stimulation and LDOPA on Balance and Motor Symptoms in Patients With Parkinson’s Disease was published online in Brain Stimulation on January 5.

Link to abstract: http://www.brainstimjrnl.com/article/S1935-861X%2814%2900398-2/abstract

Contact:
Filip Bergquist, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg
+46-702 223 664
filip.bergquist@gu.se

Weitere Informationen:

http://sahlgrenska.gu.se/english/news_and_events/news/News_Detail//portable-stim...

Henrik Axlid | idw - Informationsdienst Wissenschaft

More articles from Medical Engineering:

nachricht Surgery involving ultrasound energy found to treat high blood pressure
24.05.2018 | Queen Mary University of London

nachricht XXL computed tomography: a new dimension in X-ray analysis
17.05.2018 | Fraunhofer-Gesellschaft

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>