Cytocompatibility studies of organic light-emitting diodes (OLEDs) have been carried out on cell cultures for the first time at the Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP to test how well OLEDs are tolerated by cells. The results offer promising prospects for the use of OLEDs in the medical field, such as in light therapy. The findings were published in a white paper entitled “Preliminary cytocompatibility studies for encapsulated OLEDs” and likewise be presented at the 4th Industry Partners Day of the Fraunhofer FEP in Dresden on September 28, 2016.
Light therapy is an important means of promoting the healing of wounds. Difficult and protracted healing processes of the skin, such as are due to chronic and infected wounds, present a challenge for treating physicians and can be positively affected by exposure to light.
The Fraunhofer FEP in Dresden has years of experience researching processes, technologies, and applications for flexible OLEDs. In order to be able to employ these area light sources for potential medical applications though, any potential toxic effects caused by the constituent materials must be precluded. No such studies on what is termed the cytocompatibility of flexible OLEDs were known of to date.
Now for the first time, the cytocompatibility of flexible OLED systems has been evaluated in a pilot study. Dr. Schönfelder, head of the Medical Applications Research Group at Fraunhofer FEP, recounts enthusiastically: “Even after electrical operation and exposure to mechanical loading by bending, no toxic substances able to alter cells diffused from the OLEDs.”
As a follow-on, studies on the influence of OLED light were conducted using in vitro cell cultures from the skin and the immune system suffering from specified damage. Initial results indicate effects of accelerated auto-recovery that could be the foundation for future therapeutic applications.
Division Director Dr. Christian May in looking ahead remarks: “We need long-term studies yet to be able to guaranty cytocompatibility during exposure to OLED light. Safe electrical connections, power supplies, control circuitry, and component perimeter seals are important aspects that we are dedicating ourselves to – before direct application to the patient is allowed.”
Detailed findings can be reviewed in the white paper entitled „Preliminary cytocompatibility studies for encapsulated OLEDs“ at http://s.fhg.de/N8L and were presented by Dr. Jacqueline Hauptmann in her talk entitled “OLED light application in medicine and cytotoxicity of the materials” during the 4th Industry Partners Day devoted to medical topics at the Fraunhofer FEP on September 28, 2016.
Registration and program materials can be found at www.fep.fraunhofer.de/ipd. Sponsorship opportunities at the event as well as participation via info kiosks are available.
Annett Arnold | Fraunhofer-Institut für Organische Elektronik, Elektronenstrahl- und Plasmatechnik FEP
Biocompatible 3-D tracking system has potential to improve robot-assisted surgery
17.02.2017 | Children's National Health System
Real-time MRI analysis powered by supercomputers
17.02.2017 | University of Texas at Austin, Texas Advanced Computing Center
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
20.02.2017 | Materials Sciences
20.02.2017 | Health and Medicine
20.02.2017 | Health and Medicine