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Scaffold-Stabilized L2 Peptides: A New Approach to HPV Vaccines

The thioredoxin-L2 vaccines consist of thioredoxin as a “scaffold” protein and one of several L2 peptide concatemers. The most effective peptides have been identified by epitope mapping; a positive corre-lation of the number of peptide units in the

concatemer with the titer of neutralizing antibodies has been shown.

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