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New Monoclonal Antibodies Target Complement Proteins

Scientists at the Georg-August-University produced different monoclonal antibodies directed against components of the complement system, especially against complement factors of the alternative pathway of actiavtion, e.g. factor B and Factor D. Factor B is cleaved by factor D into the Ba component and the Bb component. together with C3b forms the alternative pathway C3 convertase C3bBb.

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