Scientists of Saarland University have recently succeeded in developing an improved series of new non-steroidal inhibitors of 17b-HSD2. Since 17b-HSD2 is…
The natural product etnangien represents a new structural type of a particularly efficient RNA polymerase inhibitor. It is effective against a broad panel of…
Over the past years in the field of forensic medicine creation of DNA profiles with biological traces has gained in importance enormously. Individual-related…
Regulated nucleo-cytoplasmic transport of pathobiologically relevant proteins is critical for tumor development and viral diseases. Transport is mediated by…
A large part of gene regulation in eukaryotes takes place at the level of RNA-molecules. A group of endogenous regulatory RNA-molecules, the so-called…
Fetal congenital lower urinary tract obstructions affect between 1:250 to 1:1000 pregnancies and are often associated with high perinatal mortality and varying…
Preterm premature rupture of membranes (PPROM) is one of the leading causes of perinatal morbidity and mortality. It complicates 3% of pregnancies and is…
Selectins (cell adhesion molecules) exhibit functional importance in pathophysiological states of the immune and cardiovascular systems which makes them…
The successful transfection or infection is a limiting factor in the development of a cell line, which is to be used for heterologous protein expression or for…
The SAPD-PCR (Specific amplified polymorphic DNA-PCR) is a species-independent detection method that allows the determination of the genetic relationship of…
Recent findings in animal models underline the potential role of the acid sphingomyelinase (aSMase) as an important drug target in inflammatory lung diseases…
The induction switch compoded by Frankfurt scientists allows for switching high current (kA range) for block voltages of 10 kV to 500 kV. This long-living…
The present invention relates to the use of a new active agent for treating allergic and atoptic dermatitis, which furthermore effects a significant abatement…
Scientists from Goethe-University Frankfurt/Main developed a therapeutic approach based on miRNA containing microvesicles allowing the prevention and treatment…
The new modulators of sphingolipid signaling enable the treatment of relapsing-remitting multiple sclerosis.Further Information: PDF INNOVECTIS Gesellschaft…
Microalgae store chemical energy as lipids including a large number of high-quality, polyunsaturated fatty acids.
Researchers from Goethe-University in…
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